Results 241 to 250 of about 1,616,867 (388)

Implementation and Evaluation of a Standard Operating Procedure for Pediatric Infliximab Infusions

, 2019
Maureen M. Kelly, Barbara Turner, Michael D. Kappelman, Eun Jeong Lee, Ajay Gulati   +4 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Infusion Thrombophlebitis

International Journal of Clinical Practice, 1970
openaire   +2 more sources

COMPARATIVE TOLERANCE TO MIXTURES OF NATURAL AND RACEMIC AMINO ACIDS ON INTRAVENOUS INFUSION IN THE DOG

, 1946
E.E. Howe, Klaus Unna, Grace Richards, A. O. Seeler   +3 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

NET BLOOD EXCHANGE OF BRANCHED-CHAIN AMINO AND α-KETO ACIDS ACROSS THE PORTAL-DRAINED VISCERA AND HINDLIMB OF CATTLE DURING INFUSIONS OF LEUCINE AND INSULIN [PDF]

, 1989
R. Early, James R. Thompson, R. J. Christopherson   +2 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

The safety of high dose continuous propofol infusion in the pediatric intensive care unit at an academic medical center. [PDF]

Front Pediatr
Fashina OA, Arteaga GM, Crow SS, Kashyap R, Frank RD, Khang X, Andrijasevic NM, Bruns DL, Wong Grossman AV.   +8 more
europepmc   +1 more source

102. Catheter-Based Intrahepatic rAAV Gene Delivery: Influence of Infusion Flow Rate and Volume on Uptake [PDF]

, 2004

openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source