Results 241 to 250 of about 105,877 (293)

Neutrophil Mobilization Triggers Microglial Functional Change to Exacerbate Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
These study underscores the pivotal role of neutrophil‐derived myeloid‐related protein 14 (MRP14) in the pathophysiology of acute ischemic stroke (AIS). MRP14 not only disrupts mitochondrial function, thereby inhibiting microglial phagocytosis of neutrophils, but also activates microglial pyroptosis, exacerbating neuroinflammation following AIS ...
Huijuan Jin, Zhifang Li, Senwei Tan, Qinghui Xiao, Qingcan Li, Jiao Ye, Yifan Zhou, Yan Wan, Qiang Liu, Bijoy K Menon, Bo Hu   +10 more
wiley   +1 more source

Response to Cojutti and Pea, "Is it Time to Move From Intermittent to Continuous Infusion Administration of Vancomycin?" [PDF]

Open Forum Infect Dis
Shiau J, Roy S, Sabourenkov P, Scheetz MH.   +3 more
europepmc   +1 more source

Implantable Biophotonic Device for Wirelessly Cancer Real‐Time Monitoring and Modulable Treatment

Advanced Science, EarlyView.
A wirelessly implantable biophotonic device is capable of distinguishing tumors and evaluating their progression by monitoring sO2 levels indicative of the tumor hypoxic microenvironment. Additionally, this device is not only employed for in situ PDT but also for concurrent monitoring of chemotherapy and PDT progress, thereby enabling the evaluation ...
Renhao Nie, Qingyan Jia, Yuanying Li, Changhan Yan, Xiyin Liu, Yaolan Tao, Jianhong Zhang, Peng Li, Wei Huang   +8 more
wiley   +1 more source

ADAPT NXT: Fixed Cycles or Every-Other-Week IV Efgartigimod in Generalized Myasthenia Gravis. [PDF]

Ann Clin Transl Neurol
Habib AA, Claeys KG, Bril V, Hussain Y, Gwathmey K, Sahagian G, Cortés-Vicente E, Brauer E, Gelinas D, Sumbul A, Jimenez RH, Hristova D, Masschaele D, Mantegazza R, Meisel A, Attarian S, ADAPT NXT Study Group.   +16 more
europepmc   +1 more source

Pancreatic Cancer‐Derived Extracellular Vesicles Enriched with miR‐223‐5p Promote Skeletal Muscle Wasting Associated with Cachexia

Advanced Science, EarlyView.
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu, Rongxi Shen, Li Zhang, Xuejin Gao, Xinbo Wang, Changhua Zhang, Xi Chen, Xinying Wang   +7 more
wiley   +1 more source

Evaluating the Impact of Smart Infusion Pump Interoperability on Reducing Medication Administration Errors: A Systematic Literature Review. [PDF]

Med Devices (Auckl)
Borrelli EP, Lucaci JD, Wilson NS, Taneja A, Weiss M, Beer I.   +5 more
europepmc   +1 more source

BCG‐Derived Outer Membrane Vesicles Induce TLR2‐Dependent Trained Immunity to Protect Against Polymicrobial Sepsis

Advanced Science, EarlyView.
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong, Wenyan Hao, Lingqi Xu, Yingyi Yang, Zhenzhen Dong, Peng Pan, Zhenjiang Bai, Jie Huang, Kaidi Yang, Zhu Jin, Rui Kang, Qiang Shan, Jiang huai Wang, Zijian Zhou, Daolin Tang, Jian Wang, Huiting Zhou   +16 more
wiley   +1 more source

Application of and research on 5G mobile nursing stations in clinical settings. [PDF]

BMC Nurs
Li C, Li L, Li J, Huang R, Qin J, Chen L, Qin F.   +6 more
europepmc   +1 more source

Long-term maintenance of remission with spacing of rituximab infusions based on the individualised patient risk profile in ANCA-associated vasculitis: a pilot study. [PDF]

RMD Open
Bartoletti A, Milanesi A, Monti S, Montecucco C, Delvino P.   +4 more
europepmc   +1 more source

Patient Preferences for Faster Home-Based Subcutaneous Immunoglobulin Infusion Therapy and the Effect on Adverse Events. [PDF]

Patient Prefer Adherence
Rutland B, Southworth C, Bosshard J.
europepmc   +1 more source