Results 61 to 70 of about 332,926 (342)

Disturbance of Vancomycin Infusion Flow during Multidrug Infusion: Influence on Endothelial Cell Toxicity

Antibiotics, 2021
Background: Phlebitis is a common side effect of vancomycin peripheral intravenous (PIV) infusion. As only one PIV catheter is frequently used to deliver several drugs to hospitalized patients through the same Y-site, perturbation of the infusion flow by
Maryline Drouet, Elodie Cuvelier, Feng Chai, Stéphanie Genay, Pascal Odou, Bertrand Décaudin   +5 more
doaj   +1 more source

True infliximab resistance in rheumatoid arthritis: a role for lymphotoxin α? [PDF]

, 2004
Background: The combination of methotrexate and the anti-tumour necrosis factor (TNF) antibody infliximab is a very effective treatment for rheumatoid arthritis (RA). However, a proportion of patients are not responsive to this treatment. Inefficacy may
Bingham, S.J., Buch, M.H., Conaghan, P., Emery, P., Quinn, M.A., Veale, D.   +5 more
core   +2 more sources

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Grape Infusions: The Flavor of Grapes and Health-Promoting Compounds in Your Tea Cup

Beverages, 2019
Traditionally, tea, a beverage made from the processed leaves of the tea plant, Camellia sinensis, and herbal infusions have been primarily consumed for their pleasant taste.
Alice Vilela, Teresa Pinto
doaj   +1 more source

Impact of intracerebroventricular enzyme replacement therapy in patients with neuronopathic mucopolysaccharidosis type II

Molecular Therapy: Methods & Clinical Development, 2021
This open-label, phase 1/2 study (JMACCT CTR JMA-IIA00350) evaluated the efficacy and safety of intracerebroventricular idursulfase beta in patients with mucopolysaccharidosis II (MPS II). Herein, we report the 100-week results.
Joo-Hyun Seo, Motomichi Kosuga, Takashi Hamazaki, Haruo Shintaku, Torayuki Okuyama   +4 more
doaj   +1 more source

Recombinant factorVIII Fc fusion protein for the prevention and treatment of bleeding in children with severe hemophilia A [PDF]

, 2015
This work was supported by funding from Biogen, including funding for the editorial and writing support in the the development of this ...
Allen, G, Barnes, C, Cristiano, LM, Gambino, G, Kulkarni, R, Liesner, R, Mahlangu, J, Neelakantan, S, Nolan, B, Pasi, J, Pierce, GF, Young, G   +11 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Bacteria as Ovipositional Attractants for \u3ci\u3eCulex Pipiens\u3c/i\u3e (Diptera: Culicidae) [PDF]

, 2017
(excerpt) The study of factors and mechanisms involving ovipositional attractants in mosquitoes is still a relatively new area of research.
Rockett, C. Lee
core   +2 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Control Volume Analysis of the Infusion Rate in Cephalic and Median Cubital Veins Based on Infusion Bag Height and Peripheral Venous Catheter Inner Diameter: Application of Bernoulli’s Equation and Consideration of Frictional Forces

Journal of Multidisciplinary Healthcare, 2023
Jeongwon Han,1 Hanna Lee2 1College of Nursing Science, Kyung Hee University, Seoul, Republic of Korea; 2Department of Nursing, Gangneung-Wonju National University, Gangwon‑do, Republic of KoreaCorrespondence: Hanna Lee, Department of Nursing, Gangneung ...
Han J, Lee H
doaj