Results 11 to 20 of about 183,426 (184)

Characterization of the polymorphism detected for the granule-bound starch synthase (WX gene) in wild einkorn wheat. [PDF]

J Sci Food Agric
Abstract BACKGROUND The WX gene encodes the granule‐bound starch synthase I or waxy protein, which is the sole enzyme responsible for amylose synthesis in wheat seeds. Wild einkorn wheat (Triticum monococcum L. ssp. aegilopoides Link em. Thell.) could be an important source of variation for this gene. RESULTS This study assessed the WX gene variability
Alvarez JB, Castellano L, Guzmán C.
europepmc   +2 more sources

Prospective Longitudinal Cohort of Argentinean Patients with Progressive Supranuclear Palsy: A Platform for Epidemiological and Translational Research [PDF]

Alzheimers Dement
Abstract Background Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are two neurodegenerative disorders that manifest disabling postural instability, parkinsonism, cognitive impairment and falls with brain neurofibrillary tangle lesions containing 4‐repeat tau protein. The prevalence is 6/100,000 inhabitants but estimated only from
Couto B, Pinto M, Avale M, Falzone T, Gershanik O, Chade A, Mizraji G, Gonzalez‐Toledo M, Peralta M, Gomez‐Arevalo G, Mezmezian M, Marras C, Sevlever G.   +12 more
europepmc   +2 more sources

Evaluación de un tapón de caucho nitrilo como sistema de envase-cierre del inmunógeno Gavac®

Revista de Investigación, Desarrollo e Innovación, 2020
Los sistemas de envase-cierre escogidos, tienen que ser compatibles con el preparado para el cual se aplican a lo largo de su período de validez. En el presente trabajo se realizó la evaluación del tapón de caucho nitrilo (RL8-9-105/0) en sustitución del
Amaury Pérez-Sánchez, Arlenis Alfaro-Martínez, Rutdali María Segura-Silva, Jesús Zamora-Sánchez, Eikel Pérez-González, Lidiana Martínez-Armas, Diasmarys Salinas-Rodríguez, Alain Moreira-Rubio   +7 more
doaj   +1 more source

Optimizing CIGB-300 intralesional delivery in locally advanced cervical cancer [PDF]

, 2015
Background:We conducted a phase 1 trial in patients with locally advanced cervical cancer by injecting 0.5 ml of the CK2-antagonist CIGB-300 in two different sites on tumours to assess tumour uptake, safety, pharmacodynamic activity and identify the ...
A Perera, A Prats, A Rodriguez-Ulloa, A Siddiqui-Jain, AM Solares, B E Acevedo, C A Casacó, C M Valenzuela, CA Naranjo, D F Alonso, F Piazza, I Baladrón, I García, I Hernández, J A Ancízar, JA Siegel, JL Soriano-García, JS Duncan, KA Ahmad, L A Torres, L González, L Molina, M A Coca, M R Sarduy, M Solares, P A López-Saura, P Therasse, R Gómez, R Prudent, RE Carter, S E Perea-Rodríguez, S Tawfic, SE Perea, SE Perea, SE Perea, V Reyes, Y M González, Y M Martínez, Y Perera, Y Perera, Y Perera, Y Perera   +41 more
core   +2 more sources

Family-specific degenerate primer design: a tool to design consensus degenerated oligonucleotides [PDF]

, 2013
Designing degenerate PCR primers for templates of unknown nucleotide sequence may be a very difficult task. In this paper, we present a new method to design degenerate primers, implemented in family-specific degenerate primer design (FAS-DPD) computer ...
Borio, Cristina Silvia, Ghiringhelli, Pablo Daniel, Goñi, Sandra Elizabeth, Iserte, Javier Alonso, Lozano, Mario Enrique, Stephan, Betina Inés   +5 more
core   +3 more sources

Developmental synaptic changes at the transient olivocochlear-inner hair cell synapse [PDF]

, 2019
In the mature mammalian cochlea, inner hair cells (IHCs) are mainly innervated by afferent fibers that convey sound information to the CNS. During postnatal development, however, medial olivocochlear (MOC) efferent fibers transiently innervate the IHCs ...
Elgoyhen, Ana Belen, Katz, Eleonora, Kearney, Graciela Inés, Vattino, Lucas Gabriel, Wedemeyer, Carolina, Zorrilla de San Martín, Javier   +5 more
core   +1 more source

Normal spatial learning and improved spatial working memory in mice (mus musculus) lacking dopamine d4 receptors [PDF]

, 2001
Dopamine terminals in the hippocampus and prefrontal cortex modulate cognitive processes such as spatial learning and working memory. Because dopamine D4 receptors are expressed in these brain areas we have analyzed mutant mice lacking this receptor ...
Avale, Maria Elena, Falzone, Tomas Luis, Gelman, Diego Matias, Rubinstein, Marcelo   +3 more
core   +1 more source

Exploring regulatory networks in plants: transcription factors of starch metabolism [PDF]

PeerJ, 2019
Biological networks are complex (non-linear), redundant (cyclic) and compartmentalized at the subcellular level. Rational manipulation of plant metabolism may have failed due to inherent difficulties of a comprehensive understanding of regulatory loops ...
Cristal López-González, Sheila Juárez-Colunga, Norma Cecilia Morales-Elías, Axel Tiessen   +3 more
doaj   +2 more sources

Time series genome-centric analysis unveils bacterial response to operational disturbance in activated sludge [PDF]

, 2019
Understanding ecosystem response to disturbances and identifying the most critical traits for the maintenance of ecosystem functioning are important goals for microbial community ecology.
Erijman, Leonardo, Figuerola, Eva Lucia Margarita, Guerrero, Leandro Demián, Orellana, Esteban, Pérez, María Victoria   +4 more
core   +1 more source

Differential Contribution of Subunit Interfaces to α 9 α 10 Nicotinic Acetylcholine Receptor Function [PDF]

, 2017
Nicotinic acetylcholine receptors can be assembled from either homomeric or heteromeric pentameric subunit combinations. At the interface of the extracellular domains of adjacent subunits lies the acetylcholine binding site, composed of a principal ...
Boffi, Juan Carlos, Bouzat, Cecilia Beatriz, Collins, Toby, Corradi, Jeremias, Craig, Patricio Oliver, Elgoyhen, Ana Belen, Gill Thind, JasKiran K., Lipovsek, Maria Marcela, Marcovich, Irina, Millar, Neil S., Moglie, Marcelo Javier, Plazas, Paola Viviana   +11 more
core   +3 more sources