Results 11 to 20 of about 3,335 (282)

Pharmacokinetics of Coencapsulated Antiretrovirals with Ingestible Sensors [PDF]

AIDS Research and Human Retroviruses, 2020
We investigated the use of a system with an ingestible sensor (Proteus Digital Health Feedback system) coencapsulated with antiretrovirals (ARVs) to measure real-time adherence. To assess the safety and impact, if any, coencapsulation might have on ARV concentrations, we evaluated the pharmacokinetics of ARVs coencapsulated with an ingestible sensor ...
Liu, Honghu, Daar, Eric, Wang, Yan, Siqueiros, Lisa, Campbell, Kayla, Shen, Jie, Guerrero, Mario, Ko, Meng-Wei, Xiong, Di, Dao, John, Young, Todd, Rosen, Marc, Fletcher, Courtney V   +12 more
openaire   +7 more sources

Gelatin‐Based Ingestible Impedance Sensor to Evaluate Gastrointestinal Epithelial Barriers

Advanced Materials, 2023
AbstractLow‐profile and transient ingestible electronic capsules for diagnostics and therapeutics can replace widely used yet invasive procedures such as endoscopies. Several gastrointestinal diseases such as reflux disease, Crohn's disease, irritable bowel syndrome, and eosinophilic esophagitis result in increased intercellular dilation in epithelial ...
Gaurav Balakrishnan, Arnav Bhat, Durva Naik, Julie Shin Kim, Sona Marukyan, Lily Gido, Mia Ritter, Aditya S. Khair, Christopher J. Bettinger   +8 more
openaire   +4 more sources

An Ingestible Sensor for Measuring Medication Adherence

IEEE Transactions on Biomedical Engineering, 2015
In this paper, we describe the design and performance of the first integrated-circuit microsensor developed for daily ingestion by patients. The ingestible sensor is a device that allows patients, families, and physicians to measure medication ingestion and adherence patterns in real time, relate pharmaceutical compliance to important physiologic ...
Hooman, Hafezi, Timothy L, Robertson, Greg D, Moon, Kit-Yee, Au-Yeung, Mark J, Zdeblick, George M, Savage   +5 more
openaire   +4 more sources

Ingestible sensors correlate closely with peripheral temperature measurements in febrile patients [PDF]

Journal of Infection, 2020
Reliable non-invasive methods for measuring body temperature are essential for the diagnosis and monitoring of infectious disease.This study used Intraclass Correlation Coefficients (ICC) and the Bland- Altman plot to analyse the agreement between temperature measurements using an ingestible capsule sensor, a skin sensor and two non-invasive peripheral
Huang, Fanyu, Magnin, Chloe, Brouqui, Philippe   +2 more
openaire   +4 more sources

Direct Adherence Measurement Using an Ingestible Sensor Compared With Self-Reporting in High-Risk Cardiovascular Disease Patients Who Knew They Were Being Measured: A Prospective Intervention

JMIR mHealth and uHealth, 2017
BackgroundUse of appropriate cardioprotective medication is a cornerstone of cardiovascular disease prevention, but less-than-optimal patient adherence is common. Thus, strategies for improving adherence are recommended to adopt a multifaceted approach.
Thompson, David, Mackay, Teresa, Matthews, Maria, Edwards, Judith, Peters, Nicholas S, Connolly, Susan B   +5 more
doaj   +2 more sources

Feasibility and accuracy of continuous intraabdominal pressure monitoring with a capsular device in human pilot trial [PDF]

World Journal of Emergency Surgery
Background Intrabdominal pressure (IAP) is an important parameter. Elevated IAP can reduce visceral perfusion, lead to intraabdominal hypertension, and result in life-threatening abdominal compartment syndrome. While ingestible capsular devices have been
Chien-Hung Liao, David A. Spain, Chih-Chi Chen, Chi-Tung Cheng, Wei-Cheng Lin, Dong-Ru Ho, Heng-Fu Lin, Fausto Catena   +7 more
doaj   +2 more sources

Preclinical study of a novel ingestible bleeding sensor for upper gastrointestinal bleeding [PDF]

Clinical Endoscopy
Background/Aims Upper gastrointestinal bleeding (UGIB) is a life-threatening condition that necessitates early identification and intervention and is associated with substantial morbidity, mortality, and socioeconomic burden.
Kimberly F. Schuster, Christopher C. Thompson, Marvin Ryou   +2 more
doaj   +3 more sources

Medication adherence assessment: high accuracy of the new Ingestible Sensor System in kidney transplants. [PDF]

Transplantation, 2013
This open-label single-arm exploratory study evaluated the accuracy of the Ingestible Sensor System (ISS), a novel technology for directly assessing the ingestion of oral medications and treatment adherence.ISS consists of an ingestible event marker (IEM), a microsensor that becomes activated in gastric fluid, and an adhesive personal monitor (APM ...
Eisenberger U, Wüthrich RP, Bock A, Ambühl P, Steiger J, Intondi A, Kuranoff S, Maier T, Green D, DiCarlo L, Feutren G, De Geest S.   +11 more
europepmc   +6 more sources

Ingestible sensor system for measuring, monitoring and enhancing adherence to antiretroviral therapy: An open-label, usual care-controlled, randomised trial. [PDF]

EBioMedicine, 2022
Liu H, Wang Y, Huang Y, Xiong D, Shen J, Siqueiros L, Bala V, Savage GM, Guerrero M, Corado K, Rosen MI, Fletcher CV, Daar ES.   +12 more
europepmc   +2 more sources

Ingestible sensor capsule with extended battery capacity allows early diagnosis of GI malignancy in comorbid patients with occult bleeding and anemia [PDF]

Endoscopy International Open
Oscar Cahyadi, Peter Ewald, Daniel Quast, Keith Siau, Waldemar Uhl, Wolfgang Schmidt, Christian Torres Reyes   +6 more
doaj   +2 more sources