Results 121 to 130 of about 572,197 (286)

Spatial distribution of radon concentration and risk evaluation through consumption of groundwater in the District of Kotli, Azad Jammu and Kashmir

open access: yesKuwait Journal of Science
Radon (222Rn) is naturally readily water-soluble, posing a cancer risk to the exposed community. Human exposure in the community may occur via 222Rn intake in drinking water.
Said Muhammad, Nizam Ullah, Alaa Ahmed
doaj   +1 more source

The effect of VC on immunoendocrine and oxidative stress responses to exercise [PDF]

open access: yes
The depression of the immune system function that is typically observed after strenuous exercise is believed to be possibly mediated by stress hormones, cytokines and oxidative stress.
بابایی, پروین   +3 more
core  

The effect of fructose and maltodextrin vs glucose and maltodextrin formulated sports beverages on mountain-bike race performance : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Sport and Exercise Science at Massey University, Wellington, New Zealand [PDF]

open access: yes, 2007
Background: Exogenous carbohydrate improves performance during prolonged high-intensity exercise. When ingested together, fructose and glucose polymers are oxidised at rates 1.5-1.7 higher than isocaloric glucose solutions.
Swift, Marilla
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Natural excretion of a metallic susceptor originating from an ingested heated tobacco stick

open access: yesClinical Case Reports
Key Clinical Message Clinicians should not only consider the presence of metallic foreign bodies within the digestive tract but also contemplate the possibility of nicotine poisoning during the diagnostic process. Abstract When clinicians encounter cases
Hirohito Doi   +3 more
doaj   +1 more source

Application of multivariate analysis to electrical penetration graphs using manual and automate waveform recognization from the planthopper Peregrinus maidis feeding on susceptible and resistant maize [PDF]

open access: yes, 2004
The stylet penetration activities of Peregrinus maidis (Ashmead) (Homoptera: Delphacidae), vector of Maize mosaic virus (MMV) and Maize stripe virus (MStV) were studied by electrical penetration graphs (DC-EPG) on resistant and susceptible maize inbred ...
Buduca, Cécile   +5 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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