Results 131 to 140 of about 303,814 (295)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Labeled ingredient composition and literature-reported hazard signals in children's toothpastes available through selected UAE retail sources. [PDF]

Front Oral Health
Manla S, Al Halabi M, Senok A, Nassar R, Salami A, Hussein I, Kowash M.   +6 more
europepmc   +1 more source

Active Ingredient Prescribing in Australia: Exploring Pharmacists’ Experiences

Background The Active Ingredient Prescribing (AIP) mandate was introduced Australia-wide on 1 February 2021. The AIP legislation makes the pharmacist a stakeholder who can provide valuable information to customers and patients.
Bowden, Michelle, Swifte, Taylah, Ndukwe, Henry   +2 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A Hierarchical Multi-Stage Machine-Learning Study on Predicting Oil and Salt in Chinese Restaurant Dishes for Nutrition Surveillance - 6 Survey Sites, China, 2019-2020. [PDF]

China CDC Wkly
Xing Y, Zhang J, Jia X, Su C, Du W, Wang H, Liu A.   +6 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Cosmetic Ingredient Review Procedures October 2010

, 2010
CIR; Cosmetic Ingredient Review
core   +1 more source

Predicting food taste with bound-driven optimization. [PDF]

Curr Res Food Sci
Tagkopoulos P, Sfondilis D, Tagkopoulos I, Zohdi T.   +3 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

An informatics framework to harmonize electronic health record medication data for managed care analytics and artificial intelligence applications. [PDF]

J Manag Care Spec Pharm
Hsu H, Gazetta G, Lu CH, Jacobs DM.
europepmc   +1 more source