Results 221 to 230 of about 138,614 (311)

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

open access: yesThe FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki   +7 more
wiley   +1 more source

Embryonal Paratesticular Rhabdomyosarcoma Masquerading as an Inguinal Hernia: A Case Report. [PDF]

open access: yesClin Case Rep
Al Kiswani S   +7 more
europepmc   +1 more source

Adipocyte‐specific NIK depletion enhances energy metabolism and glucose tolerance in mice

open access: yesThe FEBS Journal, EarlyView.
Obesity is associated with reduced energy expenditure and increased hepatic lipid accumulation. This study reveals that loss of NIK in adipocytes stimulates FGF21‐driven expression of thermogenic genes, including UCP1, and mitochondrial uncoupled respiration.
Atakan Ozcan   +8 more
wiley   +1 more source

The Psoriasis–Eczema Interface: Clinical Classification and Therapeutic Implications From a Bicentric Experience

open access: yesInternational Journal of Dermatology, EarlyView.
The psoriasis–atopic dermatitis interface: four clinical phenotypes (coexisting, overlapping, biologic‐induced eczema, dupilumab‐induced psoriasis) across 105 patients from two Italian tertiary centers. JAK inhibitors achieved the highest response rates across all phenotypes, reflecting their mechanistic rationale targeting shared JAK‐STAT downstream ...
Michela D'Agostino   +8 more
wiley   +1 more source

The Impact of Hidradenitis Suppurativa on Sexual Function: A Multicentered Cross‐Sectional Study

open access: yesInternational Journal of Dermatology, EarlyView.
Summary of a multicenter study of 522 patients with hidradenitis suppurativa (HS) evaluating quality of life, disease severity, and sexual function. HS was associated with impaired sexual function in both women and men, with pain identified as a central driver.
Defne Özkoca   +24 more
wiley   +1 more source

Catheter Ablation: Evolution and Efficiencies

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT The present review includes a discussion the goals and pitfalls of efficiency in the medical profession, a historical perspective on the evolution of catheter ablation in the field of electrophysiology (EP), and the data regarding the relationship between efficiency and outcomes in the EP lab. Focus on efficacy is critical to maximize resource
Aravind G. Kalluri, Bradley P. Knight
wiley   +1 more source

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