Results 51 to 60 of about 149,229 (299)

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Antibiotic prophylaxis in open inguinal hernia repair: a literature review and summary of current knowledge [PDF]

, 2016
More than 1 million inguinal hernia repairs are performed in Europe and the US annually. Although antibiotic prophylaxis is not required in clean, elective procedures, the routine use of implants (90% of inguinal hernia repairs are performed with mesh ...
Maciej Śmietański, Jerzy Ropel, Wojciech Makarewicz, Maciej Bobowicz, Mateusz T. Zamkowski, Michał Kąkol   +5 more
core   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Inguinal Region

, 2021
From Slide 5-21 - Inguinal Region.

core   +3 more sources

A novel technique of a laparoscopic percutaneous guide wire for extraperitoneal internal ring closure in the management of a pediatric communicating hydrocele

Frontiers in Pediatrics
ObjectiveTo investigate the novel technique of a laparoscopic percutaneous guide wire for extraperitoneal closure (LPEC) of a patent processus vaginalis (PPV) of hydrocele in the pediatric age population.MethodsA retrospective study was conducted on ...
Guojian Ding, Shuai Sun, Yuming Wang, Yang Xiaofeng, Xinxing Liu, Zhaojiao Cai, Geng Lei, Tingliang Fu, Xiaoliang Xu   +8 more
doaj   +1 more source

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

Advanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang, Yimin Gong, Jianing Li, Tianze Wu, Mingli Deng, Yannan Yang   +5 more
wiley   +1 more source

DISCOVERY OF AN UNKNOWN HERNIA–A CASE REPORT (TARIQ’S HERNIA)

Pakistan Armed Forces Medical Journal, 2019
Some hernias, e.g. Inguinal and Umbilical are so common that almost everybody is familiar with them. Whereas, there are others, e.g. Obturator and Perineal etc which are so rare that even very Senior and Experienced Surgeons hardly find once or may not ...
Ghulam Rasool Tariq, Saqib Ur Rehman, Uzma Rasool   +2 more
doaj  

Comparison of the analgesic efficacy of two different fascial blocks in patients undergoing laparoscopic inguinal hernia surgery: A randomized control trial

Journal of Anaesthesiology Clinical Pharmacology
Background and Aims: Moderate-to-severe intensity pain is reported on the first day following lower abdominal surgery. No study has compared transversus abdominis plane (TAP) block with retrolaminar block (RLB) in laparoscopic inguinal hernia surgery for
Vanita Ahuja, Aastika Mahajan, Deepak Thapa, Sukanya Mitra, Deepika Gupta, Sanjay Gupta, Rajeev Sharma, Simrandeep Singh   +7 more
doaj   +1 more source

Post-surgical pain, physical activity and satisfaction with the decision to undergo hernia surgery : a prospective qualitative investigation [PDF]

, 2013
Peer ...
Powell, Rachael, McKee, L., McKee, Lorna, Rachael Powell, Peter M. King, King, Peter M., Bruce, J., Julie Bruce, Bruce, Julie, King, P.M., Powell, R.; id_orcid, Lorna McKee   +11 more
core   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source