Results 41 to 50 of about 116,384 (303)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of Architectural and Engineering ResearchIn Algeria, the city of Oran is home to around fifty large housing estates built in the 1950s-1962, designed according to ethnic diversity, amalgamated location between the city center and the surrounding suburbs accompanied by facilities with a ...
Farah Kefif, Malek Hendel
doaj +1 more source
Fishes of the Mountain Province Section of the Ouachita River [PDF]
, 1978 A survey of the fishes of the mountain province section of the Ouachita River from the headwaters to Remmel Dam using field collections, literature records, and museum collections showed the ichthyofauna to be made up of 80 species representing 16 ...
Douglas, Neil H., Harris, John L.
core +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Cybergeo, 2018 This article analyses the ways of living and the agro-sylvo-pastoral practices of 188 families in a steppe region of the Saharan Atlas in Algeria. The rural population is henceforth sedentary.
Adel Boussaïd +3 more
doaj +1 more source
Assembling the Proofs of Ordered Model Transformations
, 2013 In model-driven development, an ordered model transformation is a nested set of transformations between source and target classes, in which each transformation is governed by its own pre and post- conditions, but structurally dependent on its parent ...
Fernández, Maribel, Terrell, Jeffrey
core +2 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Framework for capacity based sustainable design & development: towards resilient communities
Frontiers of Architectural Research, 2019 The most fundamental struggle for realizing a sustainable built environment still lies in the use of non-renewable resources in its articulation. Although efforts have been taken to increase the use of sustainable materials the vast majority of the ...
Michaël Willem Maria Smits
doaj +1 more source