Results 1 to 10 of about 742,635 (391)

Inhaled Corticosteroids [PDF]

open access: yesPharmaceuticals, 2010
Inhaled corticosteroids (ICS) are the most effective controllers of asthma. They suppress inflammation mainly by switching off multiple activated inflammatory genes through reversing histone acetylation via the recruitment of histone deacetylase 2 (HDAC2).
openaire   +5 more sources

Inhalative Anästhetika [PDF]

open access: yesDer Anaesthesist, 2013
Als inhalative Anasthetika werden Narkotika bezeichnet, die im gasformigen Zustand uber die Lungen inhaliert und anschliesend im Blut gelost an ihren Wirkort transportiert werden. Diese Form der Anasthesie wurde bereits 1847, als Athernarkose, erfolgreich demonstriert.
Deile, Martin   +2 more
openaire   +2 more sources

Oxidized carbon black nanoparticles induce endothelial damage through C-X-C chemokine receptor 3-mediated pathway

open access: yesRedox Biology, 2021
Oxidation of engineered nanomaterials during application in various industrial sectors can alter their toxicity. Oxidized nanomaterials also have widespread industrial and biomedical applications.
Nairrita Majumder   +11 more
doaj   +1 more source

Use of Portable Air Purification Systems to Eliminate Aerosol Particles from Patient Rooms

open access: yesAerosol and Air Quality Research, 2022
SARS-CoV-2 is mainly transmitted via airborne aerosols. We determined the efficacy of two different indoor air-purification systems and compared them to conventional measures of room ventilation.
Dominic Dellweg   +3 more
doaj   +1 more source

Comparison of asthma phenotypes in OVA-induced mice challenged via inhaled and intranasal routes

open access: yesBMC Pulmonary Medicine, 2019
Background The respiratory system is exposed to various allergens via inhaled and intranasal routes. Murine models of allergic lung disease have been developed to clarify the mechanisms underlying inflammatory responses and evaluate the efficacy of novel
Dong Im Kim, Mi-Kyung Song, Kyuhong Lee
doaj   +1 more source

Comparative evaluation of the mutagenicity and genotoxicity of smoke condensate derived from Korean cigarettes [PDF]

open access: yesEnvironmental Health and Toxicology, 2015
Objectives Cigarette smoking is associated with carcinogenesis owing to the mutagenic and genotoxic effects of cigarette smoke. The aim of this study was to evaluate the mutagenic and genotoxic effects of Korean cigarettes using in vitro assays.
Ha Ryong Kim   +5 more
doaj   +1 more source

KMRC011, an agonist of toll-like receptor 5, mitigates irradiation-induced tissue damage and mortality in cynomolgus monkeys

open access: yesJournal of Immunotoxicology, 2020
In the study here, the potential applicability of KMRC011 - an agonist of toll-like receptor-5 – as a countermeasure for radiation toxicities was evaluated.
Hong-Soo Lee   +11 more
doaj   +1 more source

Transcriptomics of single dose and repeated carbon black and ozone inhalation co-exposure highlight progressive pulmonary mitochondrial dysfunction

open access: yesParticle and Fibre Toxicology, 2021
Background Air pollution is a complex mixture of particles and gases, yet current regulations are based on single toxicant levels failing to consider potential interactive outcomes of co-exposures.
Quincy A. Hathaway   +8 more
doaj   +1 more source

Validation of the Arabic Severe Respiratory Insufficiency Questionnaire

open access: yesBMC Pulmonary Medicine, 2021
Background/objectives Assessment of Health-Related Quality of Life (HRQL) in patients with chronic respiratory insufficiency requiring Home Mechanical Ventilation (HMV) requires a valid measurement tool.
Marwan F. Alawieh   +5 more
doaj   +1 more source

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