Results 1 to 10 of about 732,002 (385)

Establishment of an artificial particulate matter-induced lung disease model through analyzing pathological changes and transcriptomic profiles in mice

Scientific Reports, 2023
Particulate matter (PM), an environmental risk factor, is linked with health risks such as respiratory diseases. This study aimed to establish an animal model of PM-induced lung injury with artificial PM (APM) and identify the potential of APM for ...
Dong Im Kim, Mi-Kyung Song, Ji Eun Yuk, Hyeon Jin Seo, Kyuhong Lee   +4 more
doaj   +1 more source

Formaldehyde exposure induces differentiation of regulatory T cells via the NFAT-mediated T cell receptor signalling pathway in Yucatan minipigs

Scientific Reports, 2022
The use of minipigs (Sus scrofa) as a platform for toxicological and pharmacological research is well established. In the present study, we investigated the effect of formaldehyde (FA) exposure on helper T cell-mediated splenic immune responses in ...
Jeongsik Park, Goo-Hwa Kang, Youngkyu Kim, Ju Young Lee, Jeong Ah Song, Jeong Ho Hwang   +5 more
doaj   +1 more source

A Study on the Behavior Patterns of Liquid Aerosols Using Disinfectant Chloromethylisothiazolinone/Methylisothiazolinone Solution

Molecules, 2021
This study evaluates the behavioral characteristics of components (methylisothiazolinone (MIT) and chloromethylisothiazolinone (CMIT)) contained in disinfectant solutions when they convert to liquid aerosols.
Yong-Hyun Kim, Mi-Kyung Song, Kyuhong Lee   +2 more
doaj   +1 more source

Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage

Particle and Fibre Toxicology, 2023
Background Polypropylene (PP) is used in various products such as disposable containers, spoons, and automobile parts. The disposable masks used for COVID-19 prevention mainly comprise PP, and the disposal of such masks is concerning because of the ...
Jong-Hwan Woo, Hyeon Jin Seo, Jun-Young Lee, Iljung Lee, Kisoo Jeon, Bumseok Kim, Kyuhong Lee   +6 more
doaj   +1 more source

Coconut Oil Alleviates the Oxidative Stress-Mediated Inflammatory Response via Regulating the MAPK Pathway in Particulate Matter-Stimulated Alveolar Macrophages

Molecules, 2022
Exposure to particulate matter (PM) is related to various respiratory diseases, and this affects the respiratory immune system. Alveolar macrophages (AMs), which are defenders against pathogens, play a key role in respiratory inflammation through ...
Xinyu Chen, Dong Im Kim, Hi-Gyu Moon, Minchul Chu, Kyuhong Lee   +4 more
doaj   +1 more source

Humidifier disinfectant, sodium dichloroisocyanurate (NaDCC): assessment of respiratory effects to protect workers’ health

Scientific Reports, 2021
In South Korea, it has been found that biocides used to control and eliminate harmful organisms are used as humidifier disinfectants and cause lung disease in users.
DongSeok Seo, Yong-Hoon Lee, JiMin Jo
doaj   +1 more source

Toxicological evaluation of exhaust emissions from light-duty vehicles using different fuel alternatives in sub-freezing conditions

Particle and Fibre Toxicology, 2020
Background Emissions from road traffic are under constant discussion since they pose a major threat to human health despite the increasingly strict emission targets and regulations.
Henri Hakkarainen, Päivi Aakko-Saksa, Maija Sainio, Tuukka Ihantola, Teemu J. Rönkkö, Päivi Koponen, Topi Rönkkö, Pasi I. Jalava   +7 more
doaj   +1 more source

Relationship between Cytotoxicity and Surface Oxidation of Artificial Black Carbon

Nanomaterials, 2021
The lacking of laboratory black carbon (BC) samples have long challenged the corresponding toxicological research; furthermore, the toxicity tests of engineered carbon nanoparticles were unable to reflect atmospheric BC. As a simplified approach, we have
Yen Thi-Hoang Le, Jong-Sang Youn, Hi-Gyu Moon, Xin-Yu Chen, Dong-Im Kim, Hyun-Wook Cho, Kyu-Hong Lee, Ki-Joon Jeon   +7 more
doaj   +1 more source

Assessment of respiratory and systemic toxicity of Benzalkonium chloride following a 14-day inhalation study in rats

Particle and Fibre Toxicology, 2020
Background Although biocides at low concentrations have been used to control pests, they can be more harmful than industrial chemicals as humans are directly and frequently exposed to such biocides.
Hye-Yeon Choi, Yong-Hoon Lee, Cheol-Hong Lim, Yong-Soon Kim, In-Seop Lee, Ji-Min Jo, Ha-Young Lee, Hyo-Geun Cha, Hee Jong Woo, Dong-Seok Seo   +9 more
doaj   +1 more source

Pulmonary Toxicity of Polystyrene, Polypropylene, and Polyvinyl Chloride Microplastics in Mice

Molecules, 2022
Globally, plastics are used in various products. Concerns regarding the human body’s exposure to plastics and environmental pollution have increased with increased plastic use.
Isaac Kwabena Danso, Jong-Hwan Woo, Kyuhong Lee   +2 more
doaj   +1 more source