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Dynamics of airflow in a short inhalation [PDF]

open access: yesJournal of the Royal Society Interface, 2015
During a rapid inhalation, such as a sniff, the flow in the airways accelerates and decays quickly. The consequences for flow development and convective trans- port of an inhaled gas were investigated in a subject geometry extending from the nose to the bronchi.
Alister J. Bates   +7 more
arxiv   +8 more sources

Establishment of an artificial particulate matter-induced lung disease model through analyzing pathological changes and transcriptomic profiles in mice

open access: yesScientific Reports, 2023
Particulate matter (PM), an environmental risk factor, is linked with health risks such as respiratory diseases. This study aimed to establish an animal model of PM-induced lung injury with artificial PM (APM) and identify the potential of APM for ...
Dong Im Kim   +4 more
doaj   +1 more source

Formaldehyde exposure induces differentiation of regulatory T cells via the NFAT-mediated T cell receptor signalling pathway in Yucatan minipigs

open access: yesScientific Reports, 2022
The use of minipigs (Sus scrofa) as a platform for toxicological and pharmacological research is well established. In the present study, we investigated the effect of formaldehyde (FA) exposure on helper T cell-mediated splenic immune responses in ...
Jeongsik Park   +5 more
doaj   +1 more source

Coconut Oil Alleviates the Oxidative Stress-Mediated Inflammatory Response via Regulating the MAPK Pathway in Particulate Matter-Stimulated Alveolar Macrophages

open access: yesMolecules, 2022
Exposure to particulate matter (PM) is related to various respiratory diseases, and this affects the respiratory immune system. Alveolar macrophages (AMs), which are defenders against pathogens, play a key role in respiratory inflammation through ...
Xinyu Chen   +4 more
doaj   +1 more source

Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage

open access: yesParticle and Fibre Toxicology, 2023
Background Polypropylene (PP) is used in various products such as disposable containers, spoons, and automobile parts. The disposable masks used for COVID-19 prevention mainly comprise PP, and the disposal of such masks is concerning because of the ...
Jong-Hwan Woo   +6 more
doaj   +1 more source

Humidifier disinfectant, sodium dichloroisocyanurate (NaDCC): assessment of respiratory effects to protect workers’ health

open access: yesScientific Reports, 2021
In South Korea, it has been found that biocides used to control and eliminate harmful organisms are used as humidifier disinfectants and cause lung disease in users.
DongSeok Seo, Yong-Hoon Lee, JiMin Jo
doaj   +1 more source

A Study on the Behavior Patterns of Liquid Aerosols Using Disinfectant Chloromethylisothiazolinone/Methylisothiazolinone Solution

open access: yesMolecules, 2021
This study evaluates the behavioral characteristics of components (methylisothiazolinone (MIT) and chloromethylisothiazolinone (CMIT)) contained in disinfectant solutions when they convert to liquid aerosols.
Yong-Hyun Kim   +2 more
doaj   +1 more source

Inhalation and deposition of spherical and pollen particles after middle turbinate resection in a human nasal cavity [PDF]

open access: yesRespiratory Physiology & Neurobiology Volume 294, December 2021, 103769, 2021
Middle turbinate resection significantly alters the anatomy and redistributes the inhaled air. The superior half of the main nasal cavity is opened up, increasing accessibility to the region. This is expected to increase inhalation dosimetry to the region during exposure to airborne particles.
arxiv   +1 more source

Toxicological evaluation of exhaust emissions from light-duty vehicles using different fuel alternatives in sub-freezing conditions

open access: yesParticle and Fibre Toxicology, 2020
Background Emissions from road traffic are under constant discussion since they pose a major threat to human health despite the increasingly strict emission targets and regulations.
Henri Hakkarainen   +7 more
doaj   +1 more source

Relationship between Cytotoxicity and Surface Oxidation of Artificial Black Carbon

open access: yesNanomaterials, 2021
The lacking of laboratory black carbon (BC) samples have long challenged the corresponding toxicological research; furthermore, the toxicity tests of engineered carbon nanoparticles were unable to reflect atmospheric BC. As a simplified approach, we have
Yen Thi-Hoang Le   +7 more
doaj   +1 more source

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