Results 91 to 100 of about 480,653 (295)

Diesel Exhaust Activates & Primes Microglia: Air Pollution, Neuroinflammation, & Regulation of Dopaminergic Neurotoxicity [PDF]

, 2011
BACKGROUND: Air pollution is linked to central nervous system disease, but the mechanisms responsible are poorly understood. OBJECTIVES: Here, we sought to address the brain-region-specific effects of diesel exhaust (DE) and key cellular mechanisms ...
Block, Michelle L, Duke, Laura, Johnson, Jo Anne, Kodavanti, Prasada, Kodavanti, Urmila, Levesque, Shannon, Lull, Melinda E., Stadler, Krisztian, Surace, Michael J., Taetzsch, Thomas, Wagner, Alison   +10 more
core   +1 more source

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

Physical and geometric constraints explain the labyrinth-like shape of the nasal cavity

, 2017
The nasal cavity is a vital component of the respiratory system that heats and humidifies inhaled air in all vertebrates. Despite this common function, the shapes of nasal cavities vary widely across animals.
Brenner, Michael P., Lieberman, Daniel E., Ostilla-Mónico, Rodolfo, Zwicker, David   +3 more
core   +1 more source

A new sighting study for the fixed concentration procedure to allow for gender differences [PDF]

, 2011
The fixed concentration procedure (FCP) has been proposed as an alternative to the median lethal concentration (LC50) test (organisation for economic co-operation and development (OECD) test guideline [TG] 403) for the assessment of acute inhalation ...
Charlotte Price, David Griffiths, Greiner M., Ian Indans, Nigel Stallard, Oecd., Oecd., Oecd., Philippa Edwards, Price C., Robert Guest, Stuart Creton   +11 more
core   +2 more sources

Self‐Feeding of Engineered Tissues via Controlled Glucose Release Facilitates Survival and Vascularization of Living Implants

Advanced Functional Materials, EarlyView.
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian, Iris E. Allijn, Laura Veenendaal, Nicole Bassous, Su Ryon Shin, Jeroen Leijten   +5 more
wiley   +1 more source

Prenatal cigarette smoke exposure sensitizes acetaminophen-induced liver injury by modulating miR-34a-5p in male offspring mice

Frontiers in Cell and Developmental Biology
Introduction: Cigarette smoke (CS) exacerbates the severity of diseases not only in lungs, but also in systemic organs having no direct contact with smoke.
Daram Yang, Hyuneui Jeong, Min-Seok Kim, Sang-Ik Oh, Kyuhong Lee, Jong-Won Kim, Jong-Won Kim, Bumseok Kim   +7 more
doaj   +1 more source

Criteria for the duration of anti-inflammatory therapy in children with bronchopulmonary dysplasia

Zaporožskij Medicinskij Žurnal, 2019
Objective. To develop criteria for determining the duration of anti-inflammatory therapy and indications for withdrawal of inhaled corticosteroids (ICS) in children with bronchopulmonary dysplasia (BPD). Materials and methods.
Т. І. Stepanenko, I. M. Khrystosova, H. V. Rukavytsia   +2 more
doaj   +1 more source

A Bioresorbable Neural Interface for On‐Demand Thermal Pain Block

Advanced Functional Materials, EarlyView.
Bioresorbable, implantable neural electronics provide dynamic, on‐demand thermal modulation of peripheral nerves for safe, drug‐free pain relief. A microscale thin‐film heater and temperature sensor embedded within biodegradable encapsulants enable precise temperature control via real‐time feedback.
Jeonghwan Park, Hak‐Young Ahn, Minho Seong, Taehoon Kim, Yulin Zhou, Yameng Xu, Jaehee Lee, Ritika Raj Menghani, Yujin Choi, Minsu Park, Nadir Muzaffar, Youngeun Lee, Seung Gi Seo, Jong Uk Kim, Sang Min Won, Jahyun Koo, Elena Aprea, Taeyeon Kim, Ying Yan, Matthew R. MacEwan, Wilson Z. Ray, Raudel Avila, Geumbee Lee, John A. Rogers   +23 more
wiley   +1 more source

Differences in impact on disease or lung injury depending on the physicochemical characteristics of harmful chemicals in the PAH model

Ecotoxicology and Environmental Safety
The number of individuals with underlying medical conditions has been increasing steadily. These individuals are relatively vulnerable to harmful external factors. But it has not been proven that the effects of hazardous chemicals may differ depending on
Chul-Min Park, Seulgi Jeon, Mi-Jin Yang, Min-Seok Kim   +3 more
doaj   +1 more source

Metal–Organic Frameworks for Gaseous Pollutant Management: From Capture to Neutralization and Reutilization

Advanced Functional Materials, EarlyView.
This review maps how MOFs can manage hazardous gases by combining adsorption, neutralization, and reutilization, enabling sustainable air‐pollution control. Covering chemical warfare agent simulants, SO2, NOx, NH3, H2S, and volatile organic compounds, it highlights structure‐guided strategies that boost selectivity, water tolerance, and cycling ...
Yuanmeng Tian, Zeyu Tao, Kaikai Ma, Xiaoliang Wang, Bo Yu, Yiu Wan Yip, Zhijie Chen, Jin Shang, Bin Fei   +8 more
wiley   +1 more source