Results 91 to 100 of about 334,411 (304)

Prenatal cigarette smoke exposure sensitizes acetaminophen-induced liver injury by modulating miR-34a-5p in male offspring mice

Frontiers in Cell and Developmental Biology
Introduction: Cigarette smoke (CS) exacerbates the severity of diseases not only in lungs, but also in systemic organs having no direct contact with smoke.
Daram Yang, Hyuneui Jeong, Min-Seok Kim, Sang-Ik Oh, Kyuhong Lee, Jong-Won Kim, Jong-Won Kim, Bumseok Kim   +7 more
doaj   +1 more source

Criteria for the duration of anti-inflammatory therapy in children with bronchopulmonary dysplasia

Zaporožskij Medicinskij Žurnal, 2019
Objective. To develop criteria for determining the duration of anti-inflammatory therapy and indications for withdrawal of inhaled corticosteroids (ICS) in children with bronchopulmonary dysplasia (BPD). Materials and methods.
Т. І. Stepanenko, I. M. Khrystosova, H. V. Rukavytsia   +2 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Impacts after inhalation of nano- and fine-sized titanium dioxide particles: morphological changes, translocation within the rat lung, and evaluation of particle deposition using the relative deposition index

, 2022
S.557-569A 3-week inhalation study with nano-and fine-sized titanium dioxide (TiO2) with 3, 28, and 90 days recovery time was performed in female Wistar rats.
Baumgärtner, W., Ernst, H., Schaudien, D., Creutzenberg, O., Hansen, T., Eydner, M., Rittinghausen, S.   +6 more
core   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Enlarged, activated alveolar macrophages as quantitative surrogates of disease activity in pulmonary sarcoidosis

Frontiers in Medicine
BackgroundIn pulmonary sarcoidosis, alveolar macrophages (AMs) undergo epithelioid transformation, but their quantitative morphologic characteristics and association with systemic disease markers remain incompletely defined.Research questionDo ...
Manabu Ishida, Takeshi Saraya, Nobutaka Kitamura, Koh Nakata, Haruyuki Ishii   +4 more
doaj   +1 more source

TF-343 Alleviates Diesel Exhaust Particulate-Induced Lung Inflammation via Modulation of Nuclear Factor-κB Signaling

Journal of Immunology Research, 2019
Inhalation of diesel exhaust particulate (DEP) causes oxidative stress-induced lung inflammation. This study investigated the protective effects of TF-343, an antioxidant and anti-inflammatory agent, in mouse and cellular models of DEP-induced lung ...
Dong Im Kim, Mi-Kyung Song, Seon-Hee Kim, Chan Young Park, Kyuhong Lee   +4 more
doaj   +1 more source

A NEW INHALER. [PDF]

The Lancet, 1904
n ...
openaire   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Ethanol Enhanced in Vivo Gene Delivery with Non-Ionic Polymeric Micelles Inhalation

, 2008
Modifications of both carriers and host barriers have been investigated for efficient inhalation gene delivery to lung. Here we used a biocompatible, non-ionic poly(ethyleneoxide) -poly(propyleneoxide)-poly( ethyleneoxide) (PEO-PPO-PEO) polymeric ...
Chao, Yen-Chin; Chang, Shwu-Fen; Lu, Shao-Chun; Hwang, Tzyh-Chang; Hsieh, Wei-Hsien; Liaw, Jiahorng, 張淑芬;呂紹俊   +1 more
core