Results 161 to 170 of about 481,559 (313)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Changes in Oxidative Stress, Inflammatory and Bone Metabolism Biomarkers Following Sulfurous Water Inhalation in Osteopenic Women. [PDF]

open access: yesInt J Mol Sci
Gambari L   +11 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

open access: yesAdvanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård   +19 more
wiley   +1 more source

Inhalation Therapy [PDF]

open access: yesJournal of the Royal Society of Medicine, 1980
openaire   +2 more sources

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

open access: yesAdvanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma   +16 more
wiley   +1 more source

Combined Ruyi Zhenbao Pills-Baimai Ointment Therapy on Acute Ischemic Stroke: A Multi-Arm, Randomized, Double-Blind, Placebo Controlled Clinical Study

open access: yesTherapeutics and Clinical Risk Management
Ziying Jiang,1,* Xinzuo Qin,1,* Xiao Wu,1,* Zijian Wang,1 Xinyu Wang,1 Lingqian He,1 Mingji Cuomu,2 Zhinan Mei,3 Hongping Hou,4 Haiqing Song,1 Juexian Song1 1Department of Neurology, Xuanwu Hospital, Capital Medical University ...
Jiang Z   +10 more
doaj  

Inhaled formulations for bacterial pneumonia: Strategies and advances in drug delivery. [PDF]

open access: yesBioact Mater
Wu Y   +9 more
europepmc   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

open access: yesAdvanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman   +15 more
wiley   +1 more source

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