Results 251 to 260 of about 526,857 (343)

Mortalin and PINK1/Parkin‐Mediated Mitophagy Represent Ovarian Cancer‐Selective Targets for Drug Development

Advanced Science, EarlyView.
Ovarian cancer patients with high levels of mortalin protein in their tumors have worse survival. The investigational drug SHetA2 interferes with mortalin's support of mitochondria. The resulting mitochondrial damage causes a process called mitophagy that contributes to how SHetA2 kills cancer cells. Noncancerous cells repair their mitochondria through
Vishal Chandra, Justin Garland, Rajani Rai, Donghua Zhao, Charuksha Walgama, Sadagopan Krishnan, Andrew T. Long, Tongzu Liu, Laura Adhikari, Doris M. Benbrook   +9 more
wiley   +1 more source

Exposure scenarios for human health risk assessment of nano- and microplastic particles. [PDF]

Microplast nanoplast
Lane T, Wardani I, Koelmans AA.
europepmc   +1 more source

Lung carcinomas in Sprague-Dawley rats after exposure to low doses of radon daughters, fission neutrons, or γ-rays [PDF]

, 1989
Chameaud, J., Chmelevsky, D., Kellerer, Albrecht M., Lafuma, J., Masse, R., Morin, M.   +5 more
core   +1 more source

ELECTROCARDIOGRAPHIC STUDIES DURING THE INHALATION OF 30 PER CENT CARBON DIOXIDE IN MAN

, 1959
L. MCARDLE
openalex   +1 more source

Inhalational Anaesthesia [PDF]

Postgraduate Medical Journal, 1948
openaire   +3 more sources

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

Advanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan, Yu‐Yun Ye, Pu Shen, Jie Zhang, Qian‐Fang Meng, Ying Chen, Xin Xu, Xuan‐Lin Zhang, Lang Rao, Zhi‐Jin Fan, Jian‐Xing He   +10 more
wiley   +1 more source

Knowledge, attitudes, and practices of inhalation device use among patients with chronic obstructive pulmonary disease. [PDF]

Sci Rep
Tu Y, Yao Q, Chen Y, Ren Y, Fang B, Li X, Wang C, Wang Y.   +7 more
europepmc   +1 more source

On Antiseptic Inhalations [PDF]

BMJ, 1884
openaire   +3 more sources

CXCR1 Depletion in Ly6C+ cDC2 Alleviates Acute Lung Injury via Modulation of Th17/Treg Balance

Advanced Science, EarlyView.
Pro‐inflammatory Ly6C⁺ cDC2s are identified as key effector cells mediating Cxcr1 signaling, driving the progression of ALI. Ly6C⁺ cDC2s release high levels of Il‐6 and Il‐1β, inducing Th17 differentiation. Cxcr1 deficiency reduces Il‐6 and Il‐1β production from Ly6C⁺ cDC2s through suppressing MEK1/ERK /NF‐κB signaling, thereby shifts naïve T cells ...
Shenghui Li, Wei Zhuang, Yang Wang, Hao Qin, Xichun Qin, Xianliang Yan, Xuefei Hu, Xiucheng Liu, Chang Chen   +8 more
wiley   +1 more source

The Risks Associated with Inhalation Exposure to Cosmetics and Potential for Assessment Using Lung Organoids. [PDF]

Bioengineering (Basel)
Li Y, Luo X, Hu R, Tang L, Xiang Q.
europepmc   +1 more source