Results 61 to 70 of about 480,653 (295)
Postgraduate Medical Journal, 2007 Abstract As a result of knowledge gained from the management of asthma with inhalers and nebulisers, pulmonary delivery devices for insulin have been developed. Particle size of the aerosol particularly influences drug delivery. Although several pharmaceutical companies are developing different systems, Pfizer have launched the first ...
Sujoy, Ghosh, Andrew, Collier
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Advanced Functional Materials, EarlyView.Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
Indoor Air Quality Assessment During the Use of Tobacco and Nicotine Products*
Contributions to Tobacco and Nicotine ResearchChemical toxicants released into the environment during the use of tobacco and nicotine products potentially give rise to an elevated health risk among non-users. The aim of this study was to assess the levels of a wide range of chemical toxicants in the
Wilkinson Peter J. +3 more
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Advanced Functional Materials, EarlyView.This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer +7 more
wiley +1 more source
Development of Spray-Dried Micelles, Liposomes, and Solid Lipid Nanoparticles for Enhanced Stability
PharmaceuticsObjectives: Micelles, liposomes, and solid lipid nanoparticles (SLNs) are promising drug delivery vehicles; however, poor aqueous stability requires post-processing drying methods for maintaining long-term stability.
Shradha Dattani +6 more
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Journal of Veterinary Internal Medicine, 2021 Background Inhalation treatment frequently is used in dogs and cats with chronic respiratory disease. Little is known however about the performance of delivery devices and the distribution of aerosolized drugs in the lower airways.
Alejandra Carranza Valencia +6 more
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Thermal Burns and Smoke Inhalation Injuries [PDF]
, 2015 In this pathophysiology paper, the reader is presented with a profile of an elderly patient who recently suffered thermal burns and smoke inhalation injuries as a result of a nursing home fire.
Cox, Anna
core +1 more source
Baylor University Medical Center Proceedings, 2017 Syncope can result from certain activities that trigger an exaggerated physiological response in susceptible individuals; examples include cough, laugh, and micturition syncope. We report a novel cause for syncope, that due to reflex bradycardia and asystole produced by the use of asthma inhalers.
Robert L, Rosenthal, Jay O, Franklin
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Advanced Functional Materials, EarlyView.A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz +7 more
wiley +1 more source
Higher incidence of sperm granuloma in the epididymis of C57BL/6N mice
Laboratory Animal Research, 2018 C57BL/6N mice are inbred strains widely used in biomedical research. Hence, a large amount of basic data has been accumulated. However, in the field of histopathology, spontaneous data for relatively younger mice that are used more frequently are not yet
Do-Yong Park +11 more
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