Results 61 to 70 of about 306,111 (217)

Calibration study on subchronic inhalation toxicity of man-made vitreous fibers in rats

, 2022
S.1147-1177This 3-mo inhalation study investigated the biological effects of a special-purpose glass microfiber (E-glass microfiber), the stone wool fiber MMVF21, and a new high-temperature application fiber (calcium-magnesium-silicate fiber, CMS) in ...
Bellmann, B., Muhle, H., Ernst, H., Riego Sintes, J.M., Müller, M., Creutzenberg, O., Bernstein, D.M.   +6 more
core   +1 more source

Differences in impact on disease or lung injury depending on the physicochemical characteristics of harmful chemicals in the PAH model

Ecotoxicology and Environmental Safety
The number of individuals with underlying medical conditions has been increasing steadily. These individuals are relatively vulnerable to harmful external factors. But it has not been proven that the effects of hazardous chemicals may differ depending on
Chul-Min Park, Seulgi Jeon, Mi-Jin Yang, Min-Seok Kim   +3 more
doaj   +1 more source

The effect of a "Nuisance" dust inhalation on lung clearance

, 2022
For particles which show low solubility and/or slight biological effects a general threshold limit is applied in the occupational field, e.g. 6 mg/cubic meter (FRG) and 5 mg/cubic meter (USA). In this study the effect on lung retention and lung clearance
Bellmann, B., Muhle, H., Creutzenberg, O.   +2 more
core  

Prenatal cigarette smoke exposure sensitizes acetaminophen-induced liver injury by modulating miR-34a-5p in male offspring mice

Frontiers in Cell and Developmental Biology
Introduction: Cigarette smoke (CS) exacerbates the severity of diseases not only in lungs, but also in systemic organs having no direct contact with smoke.
Daram Yang, Hyuneui Jeong, Min-Seok Kim, Sang-Ik Oh, Kyuhong Lee, Jong-Won Kim, Jong-Won Kim, Bumseok Kim   +7 more
doaj   +1 more source

Ultrastructural observation in hamster and rat lungs after chronic inhalation of cadmium compounds

, 2022
S.264-268Long-term inhalation of CdCl2 at concentrations as low as 12.6 myg Cd/cbm causes development of lung tumors in rats (4). No information, however, was available on the chronic carcinogenicity of CdO, CdS and CdSO4 which are especially relevant to
Kreft, A., Glaser, U., Heinrich, U., Lüthe, N., Paulini, I., Thiedemann, K.-U.   +5 more
core  

Ethanol Enhanced in Vivo Gene Delivery with Non-Ionic Polymeric Micelles Inhalation

, 2008
Modifications of both carriers and host barriers have been investigated for efficient inhalation gene delivery to lung. Here we used a biocompatible, non-ionic poly(ethyleneoxide) -poly(propyleneoxide)-poly( ethyleneoxide) (PEO-PPO-PEO) polymeric ...
Chao, Yen-Chin; Chang, Shwu-Fen; Lu, Shao-Chun; Hwang, Tzyh-Chang; Hsieh, Wei-Hsien; Liaw, Jiahorng, 張淑芬;呂紹俊   +1 more
core  

Enlarged, activated alveolar macrophages as quantitative surrogates of disease activity in pulmonary sarcoidosis

Frontiers in Medicine
BackgroundIn pulmonary sarcoidosis, alveolar macrophages (AMs) undergo epithelioid transformation, but their quantitative morphologic characteristics and association with systemic disease markers remain incompletely defined.Research questionDo ...
Manabu Ishida, Takeshi Saraya, Nobutaka Kitamura, Koh Nakata, Haruyuki Ishii   +4 more
doaj   +1 more source

Inhalation Injury

, 2011
Despite significant advances in wound care of patients with burn injuries, inhalation injury remains as an important contributor to morbidity and mortality in these patients.
Arash Pirat, Coşkun Araz
core  

TF-343 Alleviates Diesel Exhaust Particulate-Induced Lung Inflammation via Modulation of Nuclear Factor-κB Signaling

Journal of Immunology Research, 2019
Inhalation of diesel exhaust particulate (DEP) causes oxidative stress-induced lung inflammation. This study investigated the protective effects of TF-343, an antioxidant and anti-inflammatory agent, in mouse and cellular models of DEP-induced lung ...
Dong Im Kim, Mi-Kyung Song, Seon-Hee Kim, Chan Young Park, Kyuhong Lee   +4 more
doaj   +1 more source

Global burden of burn and inhalation injuries and future trends: analysis of a Global Burden of Disease study 1990–2021 [PDF]

Precision and Future Medicine
Purpose This study aimed to assess the global, regional, and national burdens of burns and airway injuries using Global Burden of Disease (GBD) data between 1990 and 2021, and to project future trends through 2050.
Nara Lee, Suho Jang, Youngoh Bae, Dong Won Lee, Seung Won Lee   +4 more
doaj   +1 more source