Beraprost Attenuates Starvation‐Induced Apoptosis and Protects Feline Endothelial Cells
This study established a feline endothelial cell starvation model to test the anti‐apoptotic effects of beraprost and its stereoisomers. Beraprost and beraprost‐314d reduced starvation‐induced apoptosis by inhibiting caspase‐3/7 activity and modulating Bax expression, while beraprost‐315d was less potent.
Takumi Matsuura +2 more
wiley +1 more source
Use of the TIPS Technique as a Possible Method of Acute Inhalation Toxicity Assessment. [PDF]
Saleh DM +8 more
europepmc +1 more source
Topical bupivacaine HCl applied to the ovarian pedicle during laparoscopic ovariectomy in dogs significantly reduced early postoperative UMPS pain scores and modulated antioxidant enzyme activity (SOD, CAT). However, systemic pro‐inflammatory cytokine levels (IL‐1β, IL‐6 and TNF‐α) remained unchanged between groups.
Alper Yasin Çiplak, Bülent Polat
wiley +1 more source
Simulated aquatic aging exacerbates pulmonary toxicity of graphite nanoplatelets by mechanically and chemically induced surface oxidation, enhancing oxidative potential. [PDF]
Viswanathan K +5 more
europepmc +1 more source
ABSTRACT Introduction Long‐acting injectable buprenorphine (LAIB) is increasingly used in the Criminal Justice System (CJS) for treating people with opioid use disorder; however, little is known about these patients' experiences. We aimed to understand the perspectives of participants commenced on LAIB in prison as a part of the Understanding NSW Long ...
Amelia Woods +8 more
wiley +1 more source
Pulmonary toxicity of micro- and nano polyethylene particles following intratracheal instillation in rats. [PDF]
Han HY +12 more
europepmc +1 more source
Field‐applicable low‐intensity exercise induces bronchodilation in horses with severe asthma
Abstract Background Airway dysfunction in severe equine asthma (SEA) often results in early retirement or euthanasia of affected horses. Exercise‐induced bronchodilation occurs in horses with SEA after intense treadmill exercise, but the effects of a lighter, field‐applicable, training regimen remain largely unexplored.
Sophie Mainguy‐Seers +2 more
wiley +1 more source
Advancing chemical mixture toxicity assessment using advanced in vitro NAMs: current status and future perspectives. [PDF]
Kim H, Kim D, Choi J.
europepmc +1 more source
The way forward for assessing the human health safety of cosmetics in the EU: Proceedings of Workshop 2. [PDF]
SCCS - Scientific Committee on Consumer Safety +28 more
europepmc +1 more source
Editorial: Application of new approach methodologies in toxicological assessment of next-generation tobacco and nicotine products. [PDF]
Lemus R +4 more
europepmc +1 more source

