Results 1 to 10 of about 33,975 (243)

Economic evaluation of generic inhalational bronchodilators from the Jan-Aushadi scheme versus branded alternatives [PDF]

Cost Effectiveness and Resource Allocation
Background and objectives In India, the burden of respiratory diseases has brought about a need for the use of inhalational bronchodilators, which often pose a financial strain for a significant portion of the underprivileged population.
Jerin James, Neha Pillai Vinod, Mridula Murali Manohar, Rishi Kumaran B.   +3 more
doaj   +2 more sources

Intratracheal Administration of Chloroquine-Loaded Niosomes Minimize Systemic Drug Exposure

Pharmaceutics, 2021
Pulmonary administration provides a useful alternative to oral and invasive routes of administration while enhancing and prolonging the accumulation of drugs into the lungs and reducing systemic drug exposure. In this study, chloroquine, as a model drug,
Hesham A. Saafan, Kamilia M. Ibrahim, Yasmeena Thabet, Sara M. Elbeltagy, Rana A. Eissa, Ashraf H. Ghaleb, Fathy Ibrahim, Mahmoud Elsabahy, Noura G. Eissa   +8 more
doaj   +1 more source

Correction: Adenine base editing of CFTR using receptor targeted nanoparticles restores function to G542X cystic fibrosis airway epithelial cells [PDF]

Cellular and Molecular Life Sciences
Isabelle Rose, Miriam Greenwood, Matthew Biggart, Natalie Baumlin, Robert Tarran, Stephen L. Hart, Deborah L. Baines   +6 more
doaj   +3 more sources

Effect of Preoperative Intravenous and Inhalational Dexmedetomidine on the Hemodynamic Response of Laryngoscopy: A Prospective Double-blinded Randomized Study

Journal of Research in Pharmacy Practice, 2023
Objective: Laryngoscopy induces potent noxious stimuli causing reflex autonomic activation manifested by an increase in blood pressure and heart rate (HR). Various drugs with different routes have been tried to prevent this response.
Shivanya Singh, Priyanka Gupta, Mridul Dhar, Arhan Pasha   +3 more
doaj   +1 more source

The Impact of Age and Sex on Mouse Models of Melioidosis

Pathogens, 2020
Mouse models have been used to generate critical data for many infectious diseases. In the case of Burkholderia pseudomallei, mouse models have been invaluable for bacterial pathogenesis studies as well as for testing novel medical countermeasures ...
Christopher P. Klimko, Sylvia R. Treviño, Alicia M. Moreau, Michael J. Aponte Cuadrado, Joshua R. Meyer, David P. Fetterer, Susan L. Welkos, Patricia L. Worsham, Norman Kreiselmeier, Carl Soffler, Christopher K. Cote   +10 more
doaj   +1 more source

Anesthetic exposure in perinatal period: should we still be concerned? [PDF]

Pediatric Anesthesia and Critical Care Journal (PACCJ), 2017
In the last decade perinatal medicine has batteried up primarily over the growing concern of safety of anesthe- sia in infants and children. Increasing data in rodents and primates have proved beyond doubt that anesthesia causes neurotoxicity in ...
J. Kavitha, D. Padmaja, R. Gopinath
doaj   +1 more source

Inhalational versus intravenous anesthetics during one lung ventilation in elective thoracic surgeries: A narrative review

Saudi Journal of Anaesthesia, 2021
The anesthesia regimen used during one lung ventilation (OLV) carry the potential to affect intra-operative course and post-operative outcomes, by its effects on pulmonary vasculature and alveolar inflammation.
Swapnil Parab, Sheetal Gaikwad, Saratchandra Majeti   +2 more
doaj   +1 more source

Nebulized heparin in burn patients with inhalation trauma : safety and feasibility [PDF]

, 2020
Background: Pulmonary hypercoagulopathy is intrinsic to inhalation trauma. Nebulized heparin could theoretically be beneficial in patients with inhalation injury, but current data are conflicting.
Binnekade, Jan M., Cleffken, Berry, Colpaert, Kirsten, Dixon, Barry, Glas, Gerie J., Hollmann, Markus W., Horn, Janneke, Juffermans, Nicole P., Knape, Paul, Levi, Marcel M., Loef, Bert G., Mackie, David P., Malbrain, Manu, Muller, Jan, Preckel, Benedikt, Reidinga, Auke C., Schultz, Marcus J., van der Sluijs, K.F.   +17 more
core   +2 more sources

A portable inhalational induction device provides co-operative induction of anaesthesia in preanaesthetic area for children [PDF]

Korean Journal of Anesthesiology, 2010
BackgroundWe introduce a new, simple portable inhalational induction device (PD) that provides co-operative inhalational induction of anaesthesia using N2O and subsequent sevoflurane in the preanaesthetic induction area in children.MethodsForty-five ...
Mi-Ja Yun, Hyo-Seok Na, Young Duck Shin, Jun-Sung Han, Jung-Won Hwang, Chong Soo Kim, Jin Ho Bae   +6 more
doaj   +1 more source

Effect of one minimum alveolar concentration sevoflurane with and without fentanyl on hemodynamic response to laryngoscopy and tracheal intubation

Journal of Anaesthesiology Clinical Pharmacology, 2011
Background : Drug combinations can be used for optimum obtundation of the hemodynamic response to tracheal intubation. The objective of this trial was to compare the hemodynamic response to laryngoscopy and tracheal intubation after administration of 2 ...
Anwar Hoda, Fauzia A Khan
doaj   +1 more source