Results 111 to 120 of about 33,975 (243)

Targeting Glutamate Excitotoxicity With Memantine Modulates Glial Response and Protects Motoneurons After Spinal Root Lesion

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Motoneuron axotomy induced marked neuroinflammation, synaptic withdrawal, and structural remodeling in the ventral root crush (VRC) model, characterized by intense microglial and astroglial activation and reduced synaptic coverage. Memantine treatment produced consistent, dose‐dependent neuroprotection, with maximal effects at 45 mg/kg.
Arthur Ventura Martins Leão, Gabriel Gaspar Bíscaro, Alexandre Leite Rodrigues de Oliveira, Luciana Politti Cartarozzi   +3 more
wiley   +1 more source

Comparative Efficacy of Posterior Versus Lateral Endoscopic Approaches in the Management of Complex Lumbar Disc Herniation: A Retrospective Cohort Study

Orthopaedic Surgery, Volume 18, Issue 4, Page 695-709, April 2026.
PEID and PETD both demonstrate favorable clinical efficacy in treating the three types of complex lumbar disc herniation while showing differences in the extent of decompression achieved. ABSTRACT Introduction Complex lumbar disc herniation (CLDH), including huge, migrated, and calcified variants, poses surgical challenges due to factors such as deep ...
Wentao Liu, Jialin He, Mingzhi Liu, Hongtao Ge, Guangyao Wan, Derong Xu, Chuanli Zhou   +6 more
wiley   +1 more source

Similarity and dissimilarity in alterations of the gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane.

PLoS ONE
Although sevoflurane is one of the most commonly used inhalational anesthetic agents, the popularity of desflurane is increasing to a level similar to that of sevoflurane.
Takehiro Nogi, Kousuke Uranishi, Ayumu Suzuki, Masataka Hirasaki, Tina Nakamura, Tomiei Kazama, Hiroshi Nagasaka, Akihiko Okuda, Tsutomu Mieda   +8 more
doaj   +1 more source

Smoke Inhalational Injury Due to a Domestic Fridge Blast – A Rare Case Report

Journal of Applied Sciences and Clinical Practice
Inhalational injuries that result from exposure to smoke and toxic fumes pose significant challenges in clinical practice due to their potential for causing severe respiratory compromise.
K. Surendar Reddy, Manasa Kuthadi, Alekya Papayagari, Dileep B. Kumar   +3 more
doaj   +1 more source

Adenine base editing of CFTR using receptor targeted nanoparticles restores function to G542X cystic fibrosis airway epithelial cells

Cellular and Molecular Life Sciences
The cystic fibrosis (CF) causing variant G542X harbours a premature translation stop signal in the cystic fibrosis transmembrane conductance regulator (CFTR) mRNA. This results in nonsense-mediated decay and loss of functional CFTR protein which leads to
Isabelle Rose, Miriam Greenwood, Matthew Biggart, Natalie Baumlin, Robert Tarran, Stephen L. Hart, Deborah L. Baines   +6 more
doaj   +1 more source

The effects of halothane and isoflurane on cardiovascular function in laterally recumbent horses [PDF]

, 2005
A.L. Raisis, Akaike, Bennett, Berne, Borow, Branson, Brunson, DiCorte, Diggle, Dunlop, Dyson, Johnston, K Rogers, K.J. Blissitt, L.E. Young, Little, Lunn, Madan, Peters, Raisis, Raisis, Searle, Seymour, Singer, Singer, Singer, Steffey, Steffey, Steffey, Steffey, Steffey, Taylor, V Adams, Veenman, W Henley, Wagner, Wallmeyer, Young, Young   +38 more
core   +1 more source

Beyond DNA: Epigenetics and Proteomics in Forensic Science [PDF]

, 2016
The use of genetic evidence in criminal cases is well established and has improved the public opinion and credibility of forensic science. However, several shortcomings associated with current genetic profiling techniques exist. Scientific research aimed
Eilerts, Diane F
core   +1 more source

Inhalation Toxicology

Journal of AOAC INTERNATIONAL, 1975
Abstract Two kinds of problems associated with developing standardized procedures for the safety evaluation of new compounds are identified. The first of these is the question of the desirability of using such standard methods. It is concluded that a basic set of procedures is to be recommended, but this should be supplemented with ...
openaire   +2 more sources

Nephrotoxicity of halogenated inhalational anaesthetics: Fictions and facts [PDF]

, 2002
Conzen, Peter F., Peter, Klaus, Reichle, Florian M.   +2 more
core   +1 more source

مقايسه تأثير بيهوشی کامل وريدی و بيهوشی استنشاقی بر تست عملکرد ريوی [PDF]

, 2007
زمينه و هدف: بعد از هر عمل جراحی، تغييراتی در وضعيت تستهای ريوی ايجاد می‌گردد که می‌تواند مرحله بعد از عمل را متأثر سازد؛ در ايجاد اين تغييرات، اگر چه نوع عمل جراحی و نزديکی آن به ديافراگم، بيش‌تر مؤثر است ولی عوامل ديگری از جمله تکنيک‌های بيهوشی نيز ...
آل‌نبی, میرعلی اکبر, صفائيان, رضا   +1 more
core