Results 81 to 90 of about 802 (228)

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

Assessment of mandatory declaration excipients in pediatric off label prescriptions in Spain. [PDF]

open access: yesSci Rep
Lizano-Díez I   +6 more
europepmc   +1 more source

Can a Telemedicine Program Reduce the Number of Admissions in the Second and Third Month After Hospital Discharge for an Exacerbation of COPD Compared to a Conventional Follow-up System? [PDF]

open access: yesOpen Respir Arch, 2023
Naya Prieto A   +7 more
europepmc   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma   +16 more
wiley   +1 more source

Assessment of the feed additive consisting of benzoic acid (4d210) (VevoVitall®) for weaned piglets, pigs for fattening, sows and minor porcine species for fattening and for reproduction for the renewal of its authorisation (DSM Nutritional Products Ltd). [PDF]

open access: yesEFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +18 more
europepmc   +1 more source

[Prolonged ulcerative laryngitis]. [PDF]

open access: yesHNO, 2022
Reetz S   +2 more
europepmc   +1 more source

Claustrum Involvement in New Onset Refractory Status Epilepticus: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The claustrum sign is a distinctive neuroimaging finding characterized by bilateral T2/FLAIR hyperintensity of the claustrum, one of the most interconnected regions of the human brain. It was first described in new‐onset refractory status epilepticus (NORSE) and febrile infection–related epilepsy syndrome (FIRES).
Margherita Burani   +5 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

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