Results 81 to 90 of about 8,423,921 (236)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Bio-optical Properties of Cyanobacteria Blooms in Western Lake Erie

Frontiers in Marine Science, 2017
There is a growing use of remote sensing observations for detecting and quantifying freshwater cyanobacteria populations, yet the inherent optical properties of these communities in natural settings, fundamental to bio-optical algorithms, are not well ...
Timothy S. Moore, Colleen B. Mouw, James M. Sullivan, Michael S. Twardowski, Ashley M. Burtner, Audrey B. Ciochetto, Malcolm N. McFarland, Aditya R. Nayak, Danna Paladino, Nicole D. Stockley, Thomas H. Johengen, Angela W. Yu, Steve Ruberg, Alan Weidemann   +13 more
doaj   +1 more source

Specifications of the four components used in the Ecolight model for concentration ranges, inherent optical properties and atmosphere.

, 2013
Specifications of the four components used in the Ecolight model for concentration ranges, inherent optical properties and atmosphere.
Hendrik J. van der Woerd (420870), Winfried W. C. Gieskes (420871), Marcel R. Wernand (420869)   +2 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The specific inherent optical properties of three sub-tropical and tropical water reservoirs in Queensland, Australia [PDF]

, 2010
The underwater light climate, which is a major influence on the ecology of aquatic systems, is affected by the absorption and scattering processes that take place within the water column.
Glenn Campbell, Phinn, SR, Daniel, Paul, Daniel, P, Campbell, G, Phinn, Stuart R., Paul Daniel, Campbell, Glenn, Stuart R. Phinn   +8 more
core   +1 more source

Low-loss optical single-mode waveguide platform in thin glass with wide spectral range

, 2022
Current developments are pushing the integration of optical technologies deeper into the architecture of data centers,1 a trend in which co-packaging figures prominently due to its many inherent advantages2, 3.
Wojciech Lewoczko-Adamczyk, Lewoczko-Adamczyk, Wojciech, Oliver Kirsch, Julian Schwietering, Henning Schröder, Philipp Wachholz, Schwietering, J., Wachholz, Philipp, Schröder, Henning, Kirsch, Oliver   +9 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Sensitivity of Inherent Optical Properties From Ocean Reflectance Inversion Models to Satellite Instrument Wavelength Suites

Frontiers in Earth Science, 2019
The Earth science community seeks to develop climate data records (CDRs) from satellite measurements of ocean color, a continuous data record that now exceeds 20 years.
P. Jeremy Werdell, Lachlan I. W. McKinna, Lachlan I. W. McKinna   +2 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source