Results 221 to 230 of about 1,035,048 (296)

<i>In-vivo</i> CRISPR editing for ATTR-CM: therapeutic transthyretin silencing through hepatic genome correction. [PDF]

Ann Med Surg (Lond)
Tahir A, Imtiaz E, Ali FZ, Khan MS, Mahato RK.   +4 more
europepmc   +1 more source

Actuating and Sensing Composites of Liquid Crystal Elastomers and Poly(ionic liquid)s

Advanced Functional Materials, EarlyView.
Ionic conductive, mechanically tough, flexible, and stretchable filaments of a composite material comprising a liquid crystal elastomer and a poly(ionic liquid) are produced through 3D printing, which exhibit large actuation strain under stimulation and electrical resistance variation in response to deformation or environmental condition changes. Their
Zeping Liu, Xiaofeng Zheng, Shaoxia Zhang, Long Xu, Meng Liu, Jeremy Baribeault St‐Germain, Yue Zhao   +6 more
wiley   +1 more source

Efficacy of radiotherapy combined with immunotherapy in driver gene-negative non-small cell lung cancer with brain metastases: A single-center retrospective analysis. [PDF]

J Int Med Res
Zhang Z, Li J, Zhou H, Hou L, Wang Y, Zhang M, Zhang Y, Xue X.   +7 more
europepmc   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Recent Advances in Polymer-Based Thermal Barrier Materials for Mitigating Thermal Runaway Propagation in Lithium-Ion Batteries. [PDF]

Polymers (Basel)
Li Y, Xie YY, Zhang YJ, Ma L, Bao DP, Wen SH, Liu SC, Chen ZY, Zhang GD, Ji XB, Tang LC.   +10 more
europepmc   +1 more source

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

Advanced Functional Materials, EarlyView.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova, Ivan V. Zelepukin, Lyubov V. Gorelik, Anton L. Popov, Andrei I. Pastukhov, Gleb V. Tikhonowski, Maxim S. Savinov, Danil D. Kolmanovich, Nikita A. Pivovarov, Alina Yu. Kapitannikova, Anton A. Popov, Anna S. Sogomonyan, Vsevolod A. Skribitsky, Aziz B. Mirkasymov, Andrei V. Kabashin, Sergey M. Deyev   +15 more
wiley   +1 more source

Limiting resident shifts to 16 hours is evidence informed, ethically sound. [PDF]

Can Fam Physician
Masson M.
europepmc   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Assessing the real-world safety of vutrisiran for transthyretin-mediated amyloidosis with polyneuropathy: Based on WHO-VigiAccess and FAERS databases. [PDF]

PLoS One
Tong W, Li Y, Xu X, Mao Y, Zhang R, Zhao C, Zhang J, Du C, Feng J.   +8 more
europepmc   +1 more source

Anomalous Pressure‐Temperature Ultrahigh Sensitivities in Atomically Engineered Carbonitride MXenes for Multifunctional Wearable Human–Machine Interfaces: Joint Computational–Experimental Elucidations

Advanced Functional Materials, EarlyView.
Atomically engineered layered 2D Ti3CNTz carbonitride MXene exhibits ultrahigh heat and pressure sensitivity, enabling dual‐mode sensors with 300%–400% performance enhancement and durability for real‐time health‐monitoring interface devices. Precise nitrogen incorporation (e.g., Ti3C1.8N0.2Tz) boosts conductivity, enhancing temperature response, while ...
Debananda Mohapatra, Ju‐Hyoung Han, Hyun Jin Kang, Jeong Eun Byun, Seonghun Lee, Sanghyuk Lee, Yeseul Son, Jaeeun Park, Tae Joo Shin, Youngho Kang, Jung Woo Lee, Soon‐Yong Kwon, Soo‐Hyun Kim   +12 more
wiley   +1 more source