Results 251 to 260 of about 992,612 (392)

The Inheritance of Mental Characters [PDF]

, 1902
T. D. A. Cockerell
openalex   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

Discovery of papyifuran A as an unusual cembrane diterpenoid from Boswellia papyrifera resin reveals EEF2 as a potent new drug target for fibrosis of multiple organs

Acta Pharmaceutica Sinica B
Chronic kidney disease (CKD) affects 8%–15% of the population globally and can cause renal failure, partly due to lack of effective treatments and drug targets.
Madhu Babu Sura, Yeting Zhou, Jijun Li, Yongxian Cheng   +3 more
doaj  

The Transformation Experiment of Frederick Griffith II: Inclusion of Cellular Heredity for the Creation of Novel Microorganisms. [PDF]

Bioengineering (Basel)
Müller GA.
europepmc   +1 more source

Inheritance of Face Shape in Swine

, 1930
Yoshitaka Habu
openalex   +2 more sources

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

Advanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng, Xuegang Wang, Mingjun Zhong, Jia Geng, Wenjian Li, Kanglu Pei, Jing Wang, Lanchen Wang, Yu Lu, Jing Cheng, Fengxiao Bu, Huijun Yuan   +11 more
wiley   +1 more source

Transgenerational epigenetic inheritance increases trait variation but is not adaptive. [PDF]

Evolution
Shahmohamadloo RS, Fryxell JM, Rudman SM.   +2 more
europepmc   +1 more source

Sex-linked inheritance in Drosophila

, 1916
T. H. Morgan, Calvin B. Bridges
openalex   +2 more sources

Inheritance of Melanism in Moths [PDF]

, 1931
A. W. Mckenny Hughes
openalex   +1 more source

The Neuropathic Inheritance [PDF]

Proceedings of the Royal Society of Medicine, 1913
openaire   +4 more sources