Results 261 to 270 of about 1,049,137 (382)

HIDF: Integrating Tree‐Structured scRNA‐seq Heterogeneity for Hierarchical Deconvolution of Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
The prevailing neglect of cellular hierarchies in current spatial transcriptomics deconvolution often obscures cellular heterogeneity and impedes the identification of fine‐grained subtypes. To address this issue, HIDF employs a cluster‐tree and dual regularization to systematically model cellular hierarchical structures.
Zhiyi Zou   +5 more
wiley   +1 more source

Evolutionary Divergence of an Ethylene‐Responsive Transcriptional Cascade Governs a Dose‐Dependent Balance between Cotton Fiber Length and Strength

open access: yesAdvanced Science, EarlyView.
A tunable, ethylene‐responsive cascade governing the dose‐dependent balance between fiber length and strength is unveiled. Elevated ethylene strengthens modern tetraploid cotton (G. hirsutum) fibers but elongates those of its diploid ancestor (G. arboreum). This phenotypic switch is traced to an evolutionary functional inversion of a conserved EIN3‐ERF‐
Jie Zhang   +10 more
wiley   +1 more source

Inheritance of DNA Methylation Patterns and Its Role in Modulating Allelic Expression in <i>Camellia</i> F<sub>1</sub> Hybrids. [PDF]

open access: yesPlants (Basel)
Zhang M   +9 more
europepmc   +1 more source

Mapping the Non‐Canonical Splicing Variants: Decrypting the Hidden Genetic Architecture of Idiopathic Male Infertility

open access: yesAdvanced Science, EarlyView.
This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li   +22 more
wiley   +1 more source

Maternal effects and recessive epistasis govern green, yellow and brown seed coat color inheritance in soybean [Glycine max (L.) Merr.]. [PDF]

open access: yesBiol Res
Kumar R   +9 more
europepmc   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

open access: yesAdvanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan   +12 more
wiley   +1 more source

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