Results 121 to 130 of about 27,034 (184)

Antagonistic histone post-translational modifications improve the fidelity of epigenetic inheritance - a Bayesian perspective. [PDF]

Epigenetics Chromatin
Prabhu BNB, Soni AN, Pillai SRB, Ramakrishnan N.   +3 more
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

The Role of Prenatal Neurosonography in Identification of Tubulinopathy-Narrative Review. [PDF]

Life (Basel)
Berbeka K, Stefańska K, Świetlicki A, Filipecka-Tyczka D, Rybak-Krzyszkowska M, Illa M.   +5 more
europepmc   +1 more source

Medical Reasoning With Large Language Models: A Systematic Review and Evaluation

iNew Medicine, EarlyView.
ABSTRACT Large language models (LLMs) have achieved strong performance on medical exam–style tasks, motivating growing interest in their deployment in real‐world clinical settings. However, clinical decision‐making is inherently safety‐critical, context‐dependent, and conducted under evolving evidence.
Xiaohan Ren, Chenxiao Fan, Wenyin Ma, Hongliang He, Chongming Gao, Xiaoyan Zhao, Fuli Feng   +6 more
wiley   +1 more source

A Pediatric Case of Neurodevelopmental Delay with a Familial <i>H4C11</i> Variant: Clinical Course and Diagnostic Challenges. [PDF]

J Clin Med
Tudorache E, Giurgiuveanu A, Severin E, Iordănescu II, Bulf MA.   +4 more
europepmc   +1 more source

Holistic bone developing microenvironment engineered apoptotic extracellular vesicles recapitulate multidimensional developmental signatures in adult and senile bone repair

Interdisciplinary Medicine, EarlyView.
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu, Jieyun Xu, Yuan Zhao, Xinyu Guo, Hongcheng Chen, Junlong Xue, Yong Ao, Linjun Zhang, Xiaomeng Gao, Xueli Mao, Songtao Shi, Zetao Chen   +11 more
wiley   +1 more source

Compound inheritance of EHHADH and MASP1 mutations contributes to nonsyndromic cleft lip: familial analysis and zebrafish models. [PDF]

Biol Open
Swatowska P, Odrzywolski A, Kuźniarz K, Tylzanowski P.   +3 more
europepmc   +1 more source

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

Interdisciplinary Medicine, EarlyView.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma, Jiahui Huang, Yitong Chen, Haoxuan Wang, Hang Zou, Wanghong Zhao, Zilong Deng   +6 more
wiley   +1 more source

Integrated transcriptomic and variant analysis reveals molecular mechanisms of pyrethroid resistance in a genetically homogenized Cas9 strain of Aedes aegypti. [PDF]

Arch Toxicol
Brown D, Houck R, Liu N.
europepmc   +1 more source

Towards Water, Food and Energy Security: The Global Challenges and Possible Solutions for a Holistic Vision of Sustainability

Irrigation and Drainage, EarlyView.
ABSTRACT This invited paper gives an overview of the challenges the world is facing and offers a possible solution for water and food security within the holistic integrated concept of the water–energy–food (WEF) nexus. The paper summarizes the experience the author gained through working on various research projects at national and international ...
Ragab Ragab
wiley   +1 more source