Results 221 to 230 of about 82,434 (287)

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Rapid Electrodeposition of Defect‐Tuned MOF Nanoarchitectures: Synergistic Unlocking Electrochemical Performance via Dual Modulation of Morphology and Electronic Structure

Advanced Science, EarlyView.
This work utilizes rapid electrodeposition and a competitive ligand to tailor crystal fragment/ amorphous MOF structures while Ni incorporation modulates the Co electronic environment. Their synergistic control over morphology and electronic structure accelerates reconstruction into active (oxy)hydroxides, lowers the Co3+/Co4+ oxidation potential ...
Qing Wang, Zehui Yu, Sanghwa Yoon, Zitao Yang, Bongyoung Yoo   +4 more
wiley   +1 more source

The Risk of Transmission of Genetic Prion Diseases is Greater Than 50. [PDF]

Eur J Neurol
Kortazar-Zubizarreta I, Manero-Azua A, Eraña H, Aguire U, Castilla J, Perez de Nanclares G.   +5 more
europepmc   +1 more source

Integrated Ultrasound Device for Precision Bladder Volume Monitoring via Acoustic Focusing and Machine Learning

Advanced Science, EarlyView.
We present a conformable wearable ultrasound patch for noninvasive bladder volume monitoring. A flexible PZT array combined with a concave acoustic lens concentrates acoustic energy and improves depth selectivity through the anterior pelvic wall.
Long Long Cao, Feng Wen Wang, Jingwei Xue, Fulei Liu, Ming Liang Jin   +4 more
wiley   +1 more source

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

Advanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo, Ying Yang, Zizhen Fu, Fengqi Liu, Susu Fang, Kele Xu, Shanshan Wang   +6 more
wiley   +1 more source

Clinical Characteristics and Genetic Factors in Retinitis Pigmentosa: A Retrospective Analysis of a Turkish Patient Cohort. [PDF]

Med Sci (Basel)
Demirkol A, Kendir Uguz F, Cavus NM, Demirkol I, Tsang SH.   +4 more
europepmc   +1 more source

3D‐Printed Aerogel Metamaterials with Multiple Heterogeneous Interfaces Enables Integrated Control of Microwave Field, Acoustic Field, and Thermal Field

Advanced Science, EarlyView.
The Direct‐Ink‐Writing (DIW) 3D‐printed aramid nanofibers (ANF)/carbon nanotubes (CNT)/liquid metal (LM) aerogel metamaterial demonstrates an effective and lightweight strategy to achieve polarization insensitive & ultra‐wideband microwave absorption from 2.65‐18 GHz, broadband noise reduction effect in the 2800‐6400 Hz and thermal suppression ...
Yijie Liu, Kokila Khanal, Weimeng Chu, Sreekanth Ginnaram, Yijing Zhao, Chunlin Jia, Udeshwari Jamwal, Jiaqi Tao, Lvtong Duan, Wentao Yan, Yong Yang   +10 more
wiley   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Genodermatosis among the southwestern Saudi population: The pattern and the need for a premarital genetic screening protocol. [PDF]

Saudi Med J
Alfahaad HA.
europepmc   +1 more source