Results 211 to 220 of about 306,744 (280)
Some of the next articles are maybe not open access.
Critical Reviews in Clinical Laboratory Sciences, 2006
Inherited thrombophilia can be defined as a genetically determined predisposition to the development of thromboembolic complications. Since the discovery of activated protein C resistance in 1993, several additional disorders have been described and, at present, it is possible to identify an inherited predisposition in about 60 to 70% of patients with ...
Franchini M. +4 more
openaire +5 more sources
Inherited thrombophilia can be defined as a genetically determined predisposition to the development of thromboembolic complications. Since the discovery of activated protein C resistance in 1993, several additional disorders have been described and, at present, it is possible to identify an inherited predisposition in about 60 to 70% of patients with ...
Franchini M. +4 more
openaire +5 more sources
Obstetrics and Gynecology Clinics of North America, 2006
Many inherited thrombophilias have been detected and the pathophysiologic insight has increased tremendously during the last decades. Despite, however, the overwhelming observational evidence on the association between inherited thrombophilia and several women's health issues, including VTE, thus far the implications for clinical practice are uncertain.
Coppens, Michiel +2 more
openaire +3 more sources
Many inherited thrombophilias have been detected and the pathophysiologic insight has increased tremendously during the last decades. Despite, however, the overwhelming observational evidence on the association between inherited thrombophilia and several women's health issues, including VTE, thus far the implications for clinical practice are uncertain.
Coppens, Michiel +2 more
openaire +3 more sources
Journal of Pharmacy Practice, 2014
Thrombophilia alters normal hemostasis, shifting the balance in favor of thrombus formation. Inherited conditions include factor V Leiden (FVL), prothrombin G20210A mutation, deficiencies in natural anticoagulants (antithrombin [AT], protein C, and protein S), hyperhomocysteinemia, and elevations in clotting factors (factors VIII and XI). Although FVL
Haley M, Phillippe +4 more
openaire +2 more sources
Thrombophilia alters normal hemostasis, shifting the balance in favor of thrombus formation. Inherited conditions include factor V Leiden (FVL), prothrombin G20210A mutation, deficiencies in natural anticoagulants (antithrombin [AT], protein C, and protein S), hyperhomocysteinemia, and elevations in clotting factors (factors VIII and XI). Although FVL
Haley M, Phillippe +4 more
openaire +2 more sources
Inherited thrombophilia and anticoagulant therapy for women with reproductive failure
American Journal of Reproductive Immunology, 2020Reproductive failure (RF) is the inability to conceive or to carry a pregnancy to term, and its prevalence is not negligible. Pregnancy is a prothrombotic condition, which can be abnormally exaggerated in women with thrombophilia.
A. Han, J. Han, S. K. Lee
semanticscholar +1 more source
Inherited and Acquired Thrombophilias
Reproductive Sciences, 2014Thrombophilias represent an evolving story that continues to stir controversy for care providers and obstetrical patients. The predominant thrombophilic mutations include the factor V Leiden mutation, prothrombin gene mutation G20210A, methylene tetrahydrafolate reductase C667T, and deficiencies of the natural anticoagulants proteins C and S, and ...
Rambaldi MP +3 more
openaire +4 more sources
Echocardiography, 2020
Impact of the gestational changes on cardiac contractility is not clearly defined. Our aim was to evaluate subtle changes of the right ventricular systolic function during pregnancy, assessed by new echocardiographic techniques, in a population tested ...
L. Trasca +4 more
semanticscholar +1 more source
Impact of the gestational changes on cardiac contractility is not clearly defined. Our aim was to evaluate subtle changes of the right ventricular systolic function during pregnancy, assessed by new echocardiographic techniques, in a population tested ...
L. Trasca +4 more
semanticscholar +1 more source
Therapeutic Implications of Inherited Thrombophilia in Pregnancy
American Journal of Therapeutics, 2019Background: Inherited (hereditary) thrombophilia is a genetic disorder that affects coagulation, being responsible for more than 60% of idiopathic (spontaneous or unprovoked) thromboembolic events.
L. Trasca +5 more
semanticscholar +1 more source
Journal of Maternal-Fetal & Neonatal Medicine, 2019
The term thrombophilia describes disorders associated with an increased predisposition of developing venous thromboembolism (VTE). It may be acquired, like in those with antiphospholipid syndrome or inherited.
S. Dugalić +8 more
semanticscholar +1 more source
The term thrombophilia describes disorders associated with an increased predisposition of developing venous thromboembolism (VTE). It may be acquired, like in those with antiphospholipid syndrome or inherited.
S. Dugalić +8 more
semanticscholar +1 more source
Inherited Thrombophilia and Pregnancy Complications: Should We Test?
Seminars in Thrombosis and Hemostasis, 2018Recurrent miscarriages and pregnancy-related complications cause significant stress to couples looking for successful pregnancy outcome as well as to health care professionals.
Deepa R. J. Arachchillage, M. Makris
semanticscholar +1 more source
Inherited thrombophilia and pregnancy
Current Opinion in Obstetrics and Gynaecology, 1998Inherited thrombophilia is associated with an increased risk of thrombosis. Classically it consists of protein C and protein S deficiency, activated protein C resistance and antithrombin III deficiency. In pregnancy, in addition to thrombosis, inherited thrombophilia is associated with poor obstetric outcome, including recurrent miscarriage, late fetal
J, Girling, M, de Swiet
openaire +2 more sources