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Unexplained infertility: Association with inherited thrombophilia
Thrombosis Research, 2012Unexplained infertility represents one of the most common diagnoses in fertility care. Attention is being paid to the association between inherited thrombophilia and infertility causes. In this study we investigated the prevalence of inherited thrombophilia according to infertility causes.We studied Prothrombin gene G20210A mutation, Factor V Leiden ...
FATINI, CINZIA +8 more
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Inherited Thrombophilia and Pregnancy Complications Revisited
Obstetrics & Gynecology, 2008Inherited thrombophilias are not yet established as a cause of placenta-mediated pregnancy complications, such as fetal growth restriction, preeclampsia, abruption, and pregnancy loss. An inherited thrombophilia is only one of many factors that lead to development of these diseases and is unlikely to be the unique factor that should drive management in
Rodger, Marc A. +9 more
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Inherited Fibrinogen Abnormality Causing Thrombophilia
Thrombosis and Haemostasis, 1967SummaryA family with high incidence of thrombo-embolic diseases is described. Thromboses are reported from members of 3 generations, mostly as leg vein affections, frequently complicated with pulmonal embolism. The family is also known for epileptic manifestations.Investigations of affected members gave normal values for ordinary coagulation tests ...
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Inherited thrombophilia and fetal loss
Current Opinion in Hematology, 2000Acquired thrombophilia is a well-established cause of pregnancy loss. Increasing numbers of recent observations suggest that inherited thrombophilia is not only associated with gestational thromboembolism but is also a major cause of fetal loss. This review focuses on association of fetal loss with inherited thrombophilias, including dysfibrinogenemia ...
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Inherited Antithrombin Deficiency Causing Thrombophilia
Thrombosis and Haemostasis, 1965SummaryBlood coagulation systems were studied in members of a family with remarkably high incidence of thrombo - embolic diseases. Thrombotic episodes most often occurred as deep venous thrombosis in the legs, with the first attack at the age of 10-25 years.Pro coagulant factor activities were found within normal variation ranges.Plasma antithrombin ...
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Thrombophilia can be defined as laboratory abnormalities, usually in the coagulation system, that result in a hypercoagulable state and thus predispose to thrombosis. These abnormalities may be acquired or inherited. The most clearly established form of acquired thrombophilia is the antiphospholipid anti- body syndrome.
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Genetic counseling for inherited thrombophilias
Journal of Thrombosis and Thrombolysis, 2007Genetic testing for inherited thrombophilia, including mutation analysis for factor V Leiden and prothrombin G20210A, is commonly performed. Yet, tests for inherited thrombophilia are frequently ordered inappropriately, and without proper counseling about the risks, benefits and limitations of testing.
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Inherited thrombophilia and venous thromboembolism
Best Practice & Research Clinical Obstetrics & Gynaecology, 2003Pulmonary thromboembolism (PTE) is the major cause of maternal death in the UK. Underlying PTE is the problem of deep venous thrombosis (DVT). Inherited thrombophilia will be found in about 50% of women with a personal history of venous thromboembolism (VTE), and screening for thrombophilia should be considered in women with a personal or family ...
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