Results 291 to 300 of about 4,357,163 (359)

Retrospective analysis of cutaneous immune-related adverse events following checkpoint inhibitor therapy in melanoma patients reveals increased risk associated with the HLA-B*51:01 allele. [PDF]

Cancer
DiLeo M, Oglesby S, Leung CH, Pauken KE, Farooq S, Haydu LE, Kubicki SL, Martinez R, Welborn M, Zahiruddin S, Zou J, Cao K, Patel AB.   +12 more
europepmc   +1 more source

Thiazole–driven heterocyclic hybrids as EGFR inhibitors: progress in synthesis and anticancer applications

Ancilla Dsouza, V. M. Subrahmanyam, Nitinkumar S. Shetty   +2 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

CDK4/6 inhibitor rechallenge therapy in advanced breast cancer. [PDF]

Discov Oncol
Sun Y, Zhao Y, Yu X, Qi Y, Dai X.
europepmc   +1 more source

Multidimensional Assessment of Neurological Adverse Reactions Related to PD-1 Inhibitors: A Real-World Pharmacovigilance Study. [PDF]

CNS Neurosci Ther
Hu X, Wang X, Tang B, Zhang D, Cai R, Jiang H, Lin Y, Song Y, Wang Y, Huang H, Guo D, Sun X, Fan H.   +12 more
europepmc   +1 more source

Kinetic And In Silico Evaluation Of Levamisole And Albendazole As Rat Hepatic Alkaline Phosphatase Inhibitors

Z. Lukman Abdullahi, B. Bashir AbdulGaniyu, A. Salaudeen AbdulRahman   +2 more
openalex   +1 more source

Enhancing the efficacy of VEGF inhibitors by co-inhibition of HIF in the treatment of glioblastoma. [PDF]

Apoptosis
Harbi E, Byrne YY, Bozbey HU, Tastekin D, Oncul O, Hosseiny S, Yahya D, Yildiz O, Erdogan M, Slocum AK, Mason CE, Aschner M.   +11 more
europepmc   +1 more source

Remarkable Prolongation of Irreversible APTT and Non-Significant Hemorrhage: A Rare High Titer of FVIII Inhibitor Case Report and Literature Review. [PDF]

J Clin Lab Anal
Zhang KH, Lu SS, Gao PL, Fu XY, Dong GY.
europepmc   +1 more source