Results 111 to 120 of about 19,050,316 (299)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Phthalimide Non-Inhibitory Control.

open access: yes, 2013
Phthalimide Non-Inhibitory Control.
Liya Su (23822)   +2 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Cathodal tDCS over the right prefrontal cortex and inhibitory control: Pinpointing an electrode montage to disrupt a domain-general system

open access: yes
The work reported here was supported by grants from the Spanish Ministry of Science, Innovation and Universities [PID2021-122979OBC21 to CJGA (as a co-IP) and PID2024-158913NB-I00 to JP].While many tDCS studies have focused on enhancing inhibitory ...
Gómez Ariza, Carlos J.   +1 more
core   +1 more source

Proactive and reactive inhibitory control in eating disorders

open access: yesPsychiatry Research, 2017
Altered inhibitory control has been implicated in the development and maintenance of eating disorders (ED), however it is unclear how different types of inhibitory control are affected across the EDs. We explored whether individuals with bulimia nervosa (
S. Bartholdy   +6 more
semanticscholar   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The Role Of Inhibitory Control In The Ability To Solve Problems Of University Students. El Rol Del Control Inhibitorio en la Habilidad Para Resolver Problemas de Estudiantes Universitarios

open access: yes, 2020
The aim of the present study was to analyze the role of inhibitory control in the ability to solve problems of university students. The sample consisted of 90 young people with typical development (Mage= 20.58, SD= 1.27), 39 females (43.33%) and 51 males
Ortiz Granja, Dorys Noemy   +2 more
core   +1 more source

Evidence inhibitory self-control moderates effects of habit on complex but not simple health behaviors

open access: yes
Theoretically, self-control can be considered as both a facilitator of habit development and a moderator of whether behavior occurs habitually. However, debate remains on the contexts in which such relationships are likely to occur.
Phipps, Daniel J   +4 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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