Results 111 to 120 of about 1,702,831 (300)

Visual attention deficits in schizophrenia can arise from inhibitory dysfunction in thalamus or cortex [PDF]

, 2018
Schizophrenia is associated with diverse cognitive deficits, including disorders of attention-related oculomotor behavior. At the structural level, schizophrenia is associated with abnormal inhibitory control in the circuit linking cortex and thalamus ...
Barbas, Helen, Bullock, Daniel, John, Yohan J., Zikopoulos, Basilis   +3 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Inhibition and the control of information in language, memory, and other cognitive domains

Psicológica
As individuals, we have to adjust our cognition and behavior to adapt to the environment. This adjustment involves, among other things, the functioning of a set of executive/control processes like flexibility to switch from one activity to another ...
Pedro Macizo, Teresa Bajo
doaj   +1 more source

DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy [PDF]

, 2019
Natural killer (NK) cells are lymphocytes of the innate immune response characterized by their role in the destruction of tumor cells. Activation of NK cells depend on a fine balance between activating and inhibitory signals mediated by different ...
Alonso, Corona, Arcos, María José, Bañas, Helena, Bergua, Juan M., Casas-Avilés, Ignacio, Durán, Esther, Hassouneh, Fakhri, López-Sejas, Nelson, Pera Rojas, Alejandra, Solana, Rafael, Sánchez-Correa, Beatriz, Tarazona, Raquel, Valhondo, Isabel   +12 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Controlling cluster synchronization by adapting the topology [PDF]

, 2014
We suggest an adaptive control scheme for the control of zero-lag and cluster synchronization in delay-coupled networks. Based on the speed-gradient method, our scheme adapts the topology of a network such that the target state is realized.
A. L. Fradkov, A. Rapoport, Alexander Fradkov, Anton Selivanov, D. Hebb, E. Mosekilde, Eckehard Schöll, Judith Lehnert, M. Golubitsky, P. Erdős, P. Erdős, Philipp Hövel, Y. Kuramoto   +12 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A meta-analysis of the dose–response relationship between aerobic exercise and executive function in children

Frontiers in Public Health
ObjectiveWhile existing meta-analyses of executive function focus on older adults and clinical pediatric populations, a substantial gap remains regarding typically developing children during this critical period.
Yanhua Wang, Qi Wang, Min Yang, Wenwen Li, Lu Wang, Jiaqi Fan   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Nutritional habits, inhibitory control, and emotional reactivity to healthy and unhealthy food cues in non-obese female students: insights from heart rate variability

Frontiers in Nutrition
BackgroundResearch shows that the nutritional habits of university students do not follow the national recommendations. While most studies have focused on the increased risk of overweight/obesity, avoiding unhealthy food or maintaining a normal weight ...
Michela Sarlo, Fiorella Del Popolo Cristaldi, Giulia Buodo, Carmen Belacchi   +3 more
doaj   +1 more source