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Impulsivity: a deficiency of inhibitory control?
Impulsivity has been defined as acting without thinking. Impulsivity can be quantified by impulsivity questionnaires, but also by behavioral paradigms which tax inhibitory control. Previous research has repeatedly demonstrated deficient inhibitory control in psychopathological samples characterized by low impulse control (e.g., attention-deficit ...
openaire +2 more sources
Inhibitory control in addictive behaviors: is there room for memory suppression? [PDF]
López-Caneda E, Almeida-Antunes N.
europepmc +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Role of inhibitory amino acids in control of hypoglossal motor outflow to genioglossus muscle in naturally sleeping rats [PDF]
Janna L. Morrison+6 more
openalex +1 more source
Quantifying Inhibitory Control as Externalizing Proneness: A Cross-Domain Model
N. Venables+5 more
semanticscholar +1 more source
Lizards and tortoises show evidence of low inhibitory control. [PDF]
Santacà M+4 more
europepmc +1 more source
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Inhibitory Interconnections Control Burst Pattern and Emergent Network Synchrony in Reticular Thalamus [PDF]
Vikaas S. Sohal, John R. Huguenard
openalex +1 more source
Food Inhibitory Control and Reward Responsiveness in Healthy Aging. [PDF]
Aiello M+6 more
europepmc +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source