Results 31 to 40 of about 1,212,620 (281)

A new type of shooting method for nonlinear boundary value problems

Alexandria Engineering Journal, 2013
In this article we introduce a new type of iterative method for initial value problems (IVPs). We enhance this method by using shooting techniques and interpolation for the boundary value problems. Our method is more accurate and applicable than built in
Muhammad Ahsan, Sarah Farrukh
doaj   +1 more source

Global solution to the Allen-Cahn equation with singular potentials and dynamic boundary conditions

, 2012
We prove well-posedness results for the solution to an initial and boundary-value problem for an Allen-Cahn type equation describing the phenomenon of phase transitions for a material contained in a bounded and regular domain.
Allen, Barbu, Barbu, Brezzi, Brokate, Brézis, Caginalp, Cahn, Chill, Elliott, Escher, Feng, Fischer, Gal, Gal, Gilardi, Grasselli, Grasselli, Kenzler, Lions, Luca Calatroni, Miranville, Pierluigi Colli, Schimperna, Simon, Sprekels, Wheeler   +26 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

On an Initial-boundary Value Problem Which Arises in the Dynamics of a Compressible Ideal Stratified Fluid

Известия Иркутского государственного университета: Серия "Математика"
In this paper, we investigate the problem on small motions of a compressible ideal stratified fluid in a bounded domain. The problem is studied on the base of approach connected with application of so-called operator matrices theory, as well as abstract ...
D. O. Tsvetkov
doaj   +1 more source

Global search algorithm for optimal control [PDF]

, 1970
Random-search algorithm employs local and global properties to solve two-point boundary value problem in Pontryagin maximum principle for either fixed or variable end-time problems. Mixed boundary value problem is transformed to an initial value problem.
Brocker, D. H., Kavanaugh, W. P., Stewart, E. C.   +2 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A parabolic differential equation with unbounded piecewise constant delay

International Journal of Mathematics and Mathematical Sciences, 1992
A partial differential equation with the argument [λt] is studied, where [•] denotes the greatest integer function. The infinite delay t−[λt] leads to difference equations of unbounded order.
Joseph Wiener, Lokenath Debnath
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The Well-posedness of the Null-Timelike Boundary Problem for Quasilinear Waves

, 2011
The null-timelike initial-boundary value problem for a hyperbolic system of equations consists of the evolution of data given on an initial characteristic surface and on a timelike worldtube to produce a solution in the exterior of the worldtube.
Balean R, Bishop N T, Choquet-Bruhat Y, Choquet-Bruhat Y Chruściel P T Martín-García J M, Friedlander F G, Frittelli S, H-O Kreiss, J Winicour, Kreiss H-O, Kreiss H-O, Reisswig C, Winicour J   +11 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source