Results 131 to 140 of about 27,599,660 (354)
Guidance for government offices and Education Business Link organisations : new structure for delivering education business links : establishing consortia; assessment of proposals; and criteria for awarding development funding [PDF]
, 2000 "1. This paper sets out guidance for Government Offices (GOs) on their role in: supporting the formation of new education business link consortia; assessing initial proposals; allocating development funding; and approving Initial Development Plans.
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Analysis of the effect of initial conditions on the initial development of a turbulent jet [PDF]
The effect of the initial condition at the jet exit on the downstream evolution, particularly within the potential core length, were numerically investigated as well as with available experimental data.
Cho, Ji Ryong +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Evolution of a family of expanding cubic black-hole lattices in numerical relativity
, 2013 We present the numerical evolution of a family of conformally-flat, infinite, expanding cubic black-hole lattices. We solve for the initial data using an initial-data prescription presented recently, along with a new multigrid solver developed for this ...
Bentivegna, Eloisa, Korzynski, Mikolaj
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The ITTECF and educational research: the next version of a flawed vision?
London Review of EducationIn this article we discuss the view of educational research outlined in the Initial Teacher Training and Early Career Framework (ITTECF) document, published in 2024 by the UK Department for Education, in the context of debates about the relationship ...
doaj +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source