Results 41 to 50 of about 4,524,493 (325)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Countable hyperbolic systems in the theory of nonlinear oscillations
Karpatsʹkì Matematičnì Publìkacìï, 2016 In this article a model example of a mixed problem for a fourth-order differential equation reduced to initial-boundary value problem for countable hyperbolic system of first order coherent differential equations.
T.I. Firman
doaj +1 more source
The Initial-Boundary Value Problem in General Relativity
, 2010 In this article we summarize what is known about the initial-boundary value problem for general relativity and discuss present problems related to it.Comment: 11 pages, 2 figures.
Baumgarte T. W. +9 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Using Semi-Analytic Method to Decreasing Dangers of Lead
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2016 The aim of this paper is to present a method for solving of system of first order initial value problems of ordinary differential equation by a semi-analytic technique with constructing polynomial solutions for decreasing dangers of lead.
L. N. M. Tawfiq, M. N. M. Tawfiq
doaj
On the initial value problem of a periodic box-ball system
, 2006 We show that the initial value problem of a periodic box-ball system can be solved in an elementary way using simple combinatorial methods.Comment: 9 pages, 2 ...
Jun Mada +8 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Singularity Excitations and Initial Value Problem in Continuous LTI Systems
IEEE Access, 2020 A modern challenge in electrical engineering education is to keep the math at a sufficient level, with a goal to find an optimal balance between calculus competence and operative skills needed for real-life technical applications. It is not uncommon that
Milan M. Ponjavic, Tomislav B. Sekara
doaj +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Note on a discrete initial value problem from a competition
Advances in Difference Equations, 2021 The following discrete initial value problem x n + 1 = x n ( x n − 1 2 − 2 ) − x 1 , n ∈ N , $$ x_{n+1}=x_{n}\bigl(x_{n-1}^{2}-2 \bigr)-x_{1},\quad n\in {\mathbb{N}}, $$ x 0 = 2 $x_{0}=2$ and x 1 = 5 / 2 $x_{1}=5/2$ , appeared at an international ...
Stevo Stević
doaj +1 more source