Results 41 to 50 of about 3,263,025 (375)

Caputo q-Fractional Initial Value Problems and a q-Analogue Mittag-Leffler Function [PDF]

, 2011
Caputo q-fractional derivatives are introduced and studied. A Caputo -type q-fractional initial value problem is solved and its solution is expressed by means of a new introduced q-Mittag-Leffler function. Some open problems about q-fractional integrals are proposed as well.
arxiv   +1 more source

The initial value problem for the binormal flow with rough data [PDF]

, 2013
In this article we consider the initial value problem of the binormal flow with initial data given by curves that are regular except at one point where they have a corner.
V. Banica, L. Vega
semanticscholar   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

FEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Well-posedness for weak and strong solutions of non-homogeneous initial boundary value problems for fractional diffusion equations [PDF]

arXiv, 2020
We study the well-posedness for initial boundary value problems associated with time fractional diffusion equations with non-homogenous boundary and initial values. We consider both weak and strong solutions for the problems. For weak solutions, we introduce a new definition of solutions which allows to prove the existence of solution to the initial ...
arxiv  

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

A parabolic differential equation with unbounded piecewise constant delay

International Journal of Mathematics and Mathematical Sciences, 1992
A partial differential equation with the argument [λt] is studied, where [•] denotes the greatest integer function. The infinite delay t−[λt] leads to difference equations of unbounded order.
Joseph Wiener, Lokenath Debnath
doaj   +1 more source

Initial-Value Privacy of Linear Dynamical Systems [PDF]

arXiv, 2020
This paper studies initial-value privacy problems of linear dynamical systems. We consider a standard linear time-invariant system with random process and measurement noises. For such a system, eavesdroppers having access to system output trajectories may infer the system initial states, leading to initial-value privacy risks.
arxiv  

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

Molecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock, Lina Benzien, Sandra Lange, Maja Huehns, Alexandra Runge, Catrin Roolf, Anett Sekora, Gudrun Knuebel, Hugo Murua Escobar, Christian Junghanss, Anna Richter   +10 more
wiley   +1 more source

Data‐driven performance metrics for neural network learning

International Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri, Mauro Gaggero, Marcello Sanguineti   +2 more
wiley   +1 more source