Results 41 to 50 of about 4,524,155 (277)

Note on a discrete initial value problem from a competition

Advances in Difference Equations, 2021
The following discrete initial value problem x n + 1 = x n ( x n − 1 2 − 2 ) − x 1 , n ∈ N , $$ x_{n+1}=x_{n}\bigl(x_{n-1}^{2}-2 \bigr)-x_{1},\quad n\in {\mathbb{N}}, $$ x 0 = 2 $x_{0}=2$ and x 1 = 5 / 2 $x_{1}=5/2$ , appeared at an international ...
Stevo Stević
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Runge–Kutta–Nyström Pairs of Orders 8(6) for Use in Quadruple Precision Computations

Mathematics, 2023
The second-order system of non-stiff Initial Value Problems (IVP) is considered and, in particular, the case where the first derivatives are absent.
Vladislav N. Kovalnogov, Alexander F. Matveev, Dmitry A. Generalov, Tamara V. Karpukhina, Theodore E. Simos, Charalampos Tsitouras   +5 more
doaj   +1 more source

The Initial-Boundary Value Problem in General Relativity

, 2010
In this article we summarize what is known about the initial-boundary value problem for general relativity and discuss present problems related to it.Comment: 11 pages, 2 figures.
Baumgarte T. W., Beyer H., Gustafsson B., Kreiss H. O., Nagy G., OLIVIER SARBACH, OSCAR REULA, Reula O. A., Sarbach O., Szilagyi B.   +9 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Using Semi-Analytic Method to Decreasing Dangers of Lead

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2016
         The aim of this paper is to present a method for solving of system of first order initial value problems of ordinary differential equation by a semi-analytic technique with constructing polynomial solutions for decreasing dangers of lead.
L. N. M. Tawfiq, M. N. M. Tawfiq
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

New concepts of fractional Hahn’s q,ω $q,\omega $-derivative of Riemann–Liouville type and Caputo type and applications

Advances in Difference Equations, 2018
In this paper, we give the definitions of q,ω $q,\omega $-exponential function and q,ω $q,\omega $-gamma function. New concepts of fractional Hahn’s q,ω $q,\omega $-derivative of Riemann–Liouville type and Caputo type are introduced, meanwhile we discuss
Yizhu Wang, Yiding Liu, Chengmin Hou
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source