Results 31 to 40 of about 12,954,008 (270)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Majorizing sequences for Newton's method from initial value problems [PDF]

, 2012
The most restrictive condition used by Kantorovich for proving the semilocal convergence of Newton's method in Banach spaces is relaxed in this paper, providing we can guarantee the semilocal convergence in situations that Kantorovich cannot.
Hernández, null [0000-0001-5478-2958], González, null [0000-0001-5282-7251], Ezquerro, null [0000-0001-8120-167X]   +2 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Evolutionary Derivation of Runge–Kutta Pairs of Orders 5(4) Specially Tuned for Problems with Periodic Solutions

Mathematics, 2021
The purpose of the present work is to construct a new Runge–Kutta pair of orders five and four to outperform the state-of-the-art in these kind of methods when addressing problems with periodic solutions.
Vladislav N. Kovalnogov, Ruslan V. Fedorov, Andrey V. Chukalin, Theodore E. Simos, Charalampos Tsitouras   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Efficient Semi-Analytic Technique for Solving Nonlinear Singular Initial Value Problems

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
 The aim of this paper is to present a semi - analytic technique for solving singular initial value problems of ordinary differential equations with a singularity of different kinds to construct polynomial solution using two point  osculatory ...
Luma N. M. Tawfiq, Reem W. Hussein
doaj  

Numerical Investigation of Fuzzy Predator-Prey Model with a Functional Response of the Form Arctan(ax)

Mathematics, 2021
In this paper we study a fuzzy predator-prey model with functional response arctan(ax). The fuzzy derivatives are approximated using the generalized Hukuhara derivative. To execute the numerical simulation, we use the fuzzy Runge-Kutta method.
Saed Mallak, Doa’a Farekh, Basem Attili   +2 more
doaj   +1 more source

Computability of Initial Value Problems

We demonstrate that techniques of Weihrauch complexity can be used to get easy and elegant proofs of known and new results on initial value problems. Our main result is that solving continuous initial value problems is Weihrauch equivalent to weak Kőnig's lemma, even if only solutions with maximal domains of existence are considered.
Vasco Brattka, Hendrik Smischliaew
openaire   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

On Solution of Regular Singular Initial Value Problems

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
    This paper devoted to the analysis of regular singular initial value problems for ordinary differential equations with a singularity of the first kind , we propose semi - analytic technique using two point osculatory interpolation to construct ...
Luma. N. M. Tawfiq, Reem. W. Hussein
doaj