Results 141 to 150 of about 7,177 (283)

Machine Learning‐Informed Nano Co‐Assembly Inhibits Fibroblast Activation Protein and Improves Drug Delivery in Fibrotic Tissue

open access: yesAdvanced Materials, EarlyView.
We present SP‐13786 (SP), a fibroblast activation protein (FAP) inhibitor, as a universal excipient for co‐assembling stable drug nanoparticles (SCAN). Assembly mechanism deciphered by molecular dynamics and explainable machine learning, SCAN attenuate fibrosis‐induced stromal barriers, enhances lesional drug accumulation, and improves therapeutic ...
Zehua Liu   +15 more
wiley   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton   +2 more
wiley   +1 more source

A capacitated lot-sizing model with sequence-dependent setups, parallel machines and bi-part injection moulding

open access: green, 2021
Josefa Mula   +4 more
openalex   +2 more sources

Photocatalytic Water Splitting on the Lunar Surface: Prospects for In Situ Resource Utilization

open access: yesAdvanced Materials Interfaces, EarlyView.
Water has been found in craters on the moon nearby locations which are illuminated >80% of the time. Photocatalysis uses energy from sunlight to drive chemical reactions such as water splitting to produce oxygen and hydrogen. It is a scalable technology that requires lighter equipment and utilizes resources available on the moon. ABSTRACT The discovery
Ranjani Kalyan   +6 more
wiley   +1 more source

Development of Artificial Sebaceous Gland‐Integrated In Vitro Human Skin Model

open access: yesAdvanced Materials Interfaces, EarlyView.
Uniform 3D artificial sebaceous gland spheroids, termed SebaSpheres, are generated at high throughput using a microfluidic platform and structurally integrated into a collagen‐based skin construct containing fibroblasts and keratinocytes. This work presents a modular and scalable fabrication and integration strategy for incorporating sebaceous gland ...
Daeun Ryu   +7 more
wiley   +1 more source

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