Results 181 to 190 of about 554,979 (316)

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

open access: yesAdvanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka   +2 more
wiley   +1 more source

The Formulation of Titanium - based Metal Feedstocks and the Fabrication of Parts using the Powder Injection Moulding Process

open access: yes, 2015
Development of a profitable titanium industry for New Zealand will not come about without innovative technologies. Plastic injection moulding has long held a place in NZ manufacturing to produce large quantities of complex parts and holds the key to such
Ewart, Paul Douglas
core  

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang   +17 more
wiley   +1 more source

Interfacial instabilities: implications for multi-material moulding [PDF]

open access: yes
This work investigates and identifies the mechanisms that are at work in the creation of instabilities during co-injection moulding. Two aspects are investigated, neither of which has been previously reported.
Goodship, Vannessa
core  

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni   +7 more
wiley   +1 more source

Lowered intraocular pressure in a glaucoma patient after intravitreal injection of ocriplasmin

open access: yes, 2015
Michael McClintock,1 Mathew W MacCumber1,2 1Department of Ophthalmology, Rush University Medical Center, 2Illinois Retina Associates, S.C., Chicago, IL, USA Abstract: We report the case of a glaucoma patient who received a single intravitreal ...
MacCumber MW, McClintock M
core  

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