Results 121 to 130 of about 61,590 (291)

Intramuscular injections [PDF]

, 2011
This learning resource is an example of a Umbrella learning object(ULO), and contains a series of learning objects developed by the Clinical Skills - Injections mini-project team based here at the University of Nottingham.

core  

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Effects of Intramuscular Injections of Glycosaminoglycan Polysulfates on Signs of Incipient Hip Dysplasia in Growing Dogs [PDF]

, 1992
38 pages, 1 article*Effects of Intramuscular Injections of Glycosaminoglycan Polysulfates on Signs of Incipient Hip Dysplasia in Growing Dogs* (Lust, George; Williams, Alma J.; Burton-Wurster, Nancy; Beck, Kathy A.; Rubin, Gail) 38 ...
Williams, Alma J., Rubin, Gail, Beck, Kathy A., Lust, George, Burton-Wurster, Nancy, Cornell University. Dept. of Biological Statistics and Computational Biology., Cornell University. Biometrics Unit., Cornell University. Dept. of Biometrics.   +7 more
core  

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Comparing the outcomes of in-vitro fertilization in patients receiving vaginal, subcutaneous, and intramuscular progesterone for luteal phase support: a three-armed randomized controlled trial

BMC Women's Health
Background The optimal approach to luteal-phase support in infertility treatment remains a subject of debate. This study was conducted to investigate the clinical outcomes, side effects, and patient satisfaction associated with vaginal, subcutaneous, and
Ensieh Shahrokh Tehraninejad, Sanaz Alizadeh, Elham Azimi Nekoo, Nikan Zargarzadeh, Mamak Shariat, Fedyeh Haghollahi, Azadeh Tarafdari, Mohammadamin Parsaei   +7 more
doaj   +1 more source

Difficulty and Practical Knowledge of Intramuscular Injections by Nurses in Hospitals [PDF]

, 2007
本論文は,看護師を対象とした筋肉内注射技術に関する質問紙調査を行った結果と,筋肉内注射場面の観察調査の結果及び看護師を対象とした面接調査の結果から,看護師の行う筋肉内注射技術の実践知を明らかにすること,看護師が捉えている困難点から筋肉内注射技術の課題を明らかにすることを目的とした.その結果出された結論は以下である.1.注射針の刺入深度については多くの看護師は「3分の2刺す」「2分の1刺す」と一律に答えているため,筋肉内注射部位の皮下組織厚をどのようにアセスメントしているかは不明である ...
村上, 繁子, イシダ, ヨウコ, 3068, Murakami, Shigeko, 3067, 3066, 菊池, 和子, 小山, 奈都子, Kikuchi, Kazuko, Ishida, Yoko, ムラカミ, シゲコ, Oyama, Natsuko, 菊池, 久美子, Kikuchi, Kumiko, 石田, 陽子, 3071, Takano, Naoko, 3070, オヤマ, ナツコ, 3079, 3078, 3077, 3076, 3075, 3074, 高橋, 有里, 3073, 3072, キクチ, クミコ, キクチ, カズコ, タカノ, ナオコ, タカハシ, ユウリ, 高野, 直子, 3069, Takahashi, Yuri   +34 more
core   +1 more source

MT‐RNR1 genotype testing for preventing aminoglycoside‐mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott, Sian Hilton, Cinzia Dello Russo, Nicola Booth, Simon Drysdale, Philip Howard, Stephen Hughes, Mallinath Chakraborty, Helen McDevitt, Charlotte Alston, Maya Desai, Mike Beadsworth, Adam Reynolds, Serim Min, Katherine Payne, Munir Pirmohamed, William G. Newman   +16 more
wiley   +1 more source

Poly(lactic‐co‐glycolic acid) microsphere loaded dissolving microneedles for sustained and coordinated transdermal delivery of desogestrel and ethinyl estradiol

Bulletin of the Korean Chemical Society, EarlyView.
PLGA‐based sustained‐release microneedles were developed for the delivery of desogestrel and ethinyl estradiol. The system enabled coordinated release of both drugs, suggesting its potential to improve dosing convenience as a long‐acting contraceptive platform.
Young‐Jin Kim, Byeongsu Kim, Sokyoung Joo, So‐Jeong Jeong, Chang‐Soo Han, Chun‐Woong Park   +5 more
wiley   +1 more source

Intramuscular Injection sites (for adults) [PDF]

, 2011
Intramuscular Injection sites (for adults) is designed to help you correctly identify which muscles may be used to safely administer intramuscular injections.

core