Results 181 to 190 of about 61,590 (291)

Cancer Vaccine Development: Toward Artificial Intelligence‐Assisted Personalized Cell Membrane Nanovaccine

open access: yesSmall, EarlyView.
Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley   +1 more source

Applications of chitosan derivatives as adjuvants for nanoparticle‐based vaccines: A comprehensive review

open access: yesSmart Molecules, EarlyView.
This review highlights how chitosan derivatives enhance nanoparticle‐based vaccines through superior stability, mucoadhesion, and immune modulation. By triggering robust mucosal, humoral, and cellular responses, these biocompatible polymers serve as a transformative platform for next‐generation immunotherapeutics and safe and effective vaccine delivery
Sayantani Dasgupta   +8 more
wiley   +1 more source

An observational study on the effects of as-needed use of various antipsychotic drugs for agitation due to psychotic disorders. [PDF]

open access: yesInt Clin Psychopharmacol
Hatta K   +10 more
europepmc   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

open access: yesSmart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang   +8 more
wiley   +1 more source

Injectable Zein‐Based Photothermal Composite Hydrogel Enhances Osteoporotic Tendon–Bone Healing

open access: yesSmall Methods, EarlyView.
Schematic illustration of the Zein‐based, dopamine‐grafted, niacin‐loaded carbon nanosphere (ZDC) composite hydrogel for enhancing healing of osteoporotic rotator cuff tears. This electron beam‐modified composite hydrogel is designed for NIR‐responsive release of niacin, which alleviates inflammation, promotes angiogenesis, and facilitates the ...
Kai Ye   +5 more
wiley   +1 more source

Overview of the Current Osteoarthritis Treatment in Veterinary Medicine and Future Directions. [PDF]

open access: yesACS Pharmacol Transl Sci
Quintão NLM   +6 more
europepmc   +1 more source

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