Results 41 to 50 of about 61,441 (292)

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

A First Semimanual Device for Clinical Intramuscular Repetitive Cell Injections

Cell Transplantation, 2010
Intramuscular cell transplantation in humans requires so far meticulous repetitive cell injections. Performed percutaneously with syringes operated manually, the procedure is very time consuming and requires a lot of concentration to deliver the cells ...
Pierre-Luc Richard, Clément Gosselin, Thierry Laliberté, Martin Paradis, Marlyne Goulet, Jacques P. Tremblay, Daniel Skuk M.D.   +6 more
doaj   +1 more source

Magnetic Resonance Imaging Used to Define the Optimum Needle Length in Pigs of Different Ages

Animals, 2022
Intramuscular injections result in tissue destruction and alteration. Therefore, it is necessary to evaluate the optimum injection point for intramuscular injections.
Maren Bernau, Ulrike Gerster, Armin Manfred Scholz   +2 more
doaj   +1 more source

Basic Practical Skills: Subcutaneous, Intramuscular and Intradermal Injections in Adults

, 2023
Basic practical skills: subcutaneous, intramuscular, and intradermal injection techniques in adults Learn the anatomy relevant to subcutaneous (SC), intramuscular (IM), and intradermal (ID) injection techniques, and the procedure for each injection ...
Ogston-Tuck, Sherri, BMJ Learning editors   +1 more
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Multipl MRSA Absesses Following Intramuscular Injection a Case Report

Namık Kemal Tıp Dergisi
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) cases are rarely reported. In this article, we present a patient who had no history of disease or risk factors for MRSA but developed multiple MRSA abscesses after receiving ...
Bahar Büşra ÖZKAN, Özgür GÜNAL, Hatice ÜDÜRGÜCÜ, Süleyman Sırrı KILIÇ   +3 more
doaj   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

ESTUDO EXPERIMENTAL DAS RELAÇÕES TECLDUAIS EM RATOS, PROVOCADAS POR DIFERENTES CONCENTRAÇÕES DE PENICILINA G. BENZATINA

Revista da Escola de Enfermagem da USP
A procura de respostas científicas aos problemas decorrentes de procedimentos que envolvem ações profissionais constituem um desafio constante aos enfermeiros comprometidos com a melhoria do cuidado de enfermagem.
Mara Rita Rodrigues Massad, Eduardo Massad, Edna Apparecida Moura Arcuri   +2 more
doaj   +1 more source

Paediatric Intramuscular Injections for Developing World Settings: A Review of the Literature for Best Practices

, 2023
This article examines the available evidence about intramuscular injection techniques to generate simple evidence-based or best practice guidelines for implementation in the developing world.
M C N Walters (13477174), Jeremy Furyk (13069986)   +1 more
core  

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source