Results 131 to 140 of about 2,120,753 (335)

Drug compatibility with various closed intravenous infusion containers

Frontiers in Pharmacology
Objective: The aim was to systematically compare the drug compatibility with various closed intravenous (i.v.) infusion containers, to provide a reference for selecting a relatively superior infusion container and improve the medication safety for ...
Chang-yu Zhu, Chang-yu Zhu, Hui-ying Zuo, Hong-lin Li, Rong-sheng Tong, Rong-sheng Tong   +5 more
doaj   +1 more source

US-guided botulinum toxin injection for excessive drooling in children

Diagnostic and Interventional Radiology, 2013
PURPOSEWe aimed to evaluate the safety and efficacy of botulinum toxin A (BTX-A) injections under ultrasonography (US) guidance for children with excessive drooling.
Türkmen Çiftçi, Devrim Akıncı, Nursel Yurttutan, Okan Akhan   +3 more
doaj   +1 more source

Meta-analysis of preclinical studies of mesenchymal stromal cells to treat rheumatoid arthritis. [PDF]

, 2019
BackgroundThis study aims to evaluate the quality of preclinical data, determine the effect sizes, and identify experimental measures that inform efficacy using mesenchymal stromal (or stem) cells (MSC) therapy in animal models of rheumatoid arthritis ...
Farhoodi, Henry P, Han, Menglu, Liao, Wenbin, Liu, Guangyang, Liu, Linan, Liu, Yongjun, Wong, Chi W, Zhao, Weian   +7 more
core  

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Reinforced Polymer–Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab

Advanced Healthcare Materials, EarlyView.
Biologic therapy development is rapidly accelerating, requiring extended delivery formulation strategies. Supramolecular hydrogels and electrostatic complexation create subcutaneous depots that release clinically relevant trastuzumab doses in a controlled manner through simple component mixing without chemical modifications.
Giovanni Bovone, Stéphane Bernhard, Guillaume Jacquot, Vincent Mittelheisser, Céline Mirjolet, Elia A. Guzzi, Lorenza Garau Paganella, Luca Liebi, Julien Draussin, Pedro Lopez Navarro, Elsa Barbé, Olivier Lefebvre, Jacky G. Goetz, Loic J. Charbonnière, Xavier Pivot, Sébastien Harlepp, Mark W. Tibbitt, Alexandre Detappe   +17 more
wiley   +1 more source

17β-Estradiol Potentiates the Reinstatement of Cocaine Seeking in Female Rats: Role of the Prelimbic Prefrontal Cortex and Cannabinoid Type-1 Receptors [PDF]

, 2018
Clinical observations imply that female cocaine addicts experience enhanced relapse vulnerability compared with males, an effect tied to elevated estrogen phases of the ovarian hormone cycle.
Barron, Laura M., DeBaker, Margot C., Doncheck, Elizabeth M., Frick, Karyn M., Hillard, Cecilia J, Liddiard, Gage T., Mantsch, John, Tuscher, Jennifer J., Urbanik, Luke A.   +8 more
core   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Assessment of the Toxicity and the Stability of Saeng Mak San by Using Repeated Intravenous Injections in Sprague-Dawley Rats

Journal of Pharmacopuncture, 2016
Objectives: This study used repeated intravenous injections of Saeng Maek San (SMS) injection in Sprague-Dawley (SD) rats to assess the toxicity and the stability of SMS Methods: Six-week-old male and female SD rats reared by Orient bio Inc were chosen ...
Hwa-Young Lee, Sungchul Kim, Seung-Hun Cho   +2 more
doaj   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

Advanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun, Jiachen Lin, Chenyang Xue, Yuyan Wang, Peiru Chen, Yun Wei, Guobin Xu, Anais Sidonia, Chris Nenopoulos, Hossam Tashkandi, Caroline Shen, Allison Wang, Alex Wang, Ke Zhang   +13 more
wiley   +1 more source

In Vitro Fertilization Using Luteinizing Hormone-Releasing Hormone Injections Resulted in Healthy Triplets without Increased Attack Rates in a Hereditary Angioedema Case

Case Reports in Immunology, 2018
Hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE) is a rare, autosomal dominant disorder. The management of pregnant patients with C1-INH-HAE is a challenge for the physician.
Ceyda Tunakan Dalgıç, Fatma Düşünür Günsen, Gökten Bulut, Emine Nihal Mete Gökmen, Aytül Zerrin Sin   +4 more
doaj   +1 more source