Results 61 to 70 of about 2,513 (245)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Some methods for constructing some classes of graceful uniform trees
Indonesian Journal of Combinatorics, 2018 A tree T(V, E) is graceful if there exists an injective function f from the vertex set V(T) into the set {0, 1, 2, ..., ∣V∣ − 1} which induces a bijective function fʹ from the edge set E(T) onto the set {1, 2, ..., ∣E∣}, with fʹ(uv) = ∣f(u) − f(v)∣ for ...
I Nengah Suparta +1 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Mathematical Modelling and Analysis, 1997 In this paper we study the existence and multiplicity solutions of nonlinear elliptic problem of the form Here Ω is a smooth and bounded domain in RN , N ≥ 2, λ ∈ R and f : R → R is a continuous, even function satisfying the following condition
Jan Beczek
doaj +1 more source
Injectable fillers: current status, physicochemical properties, function mechanism, and perspectives
, 2023 Jiahong Guo, Wei Fang, Feifei Wang
openalex +2 more sources
Neural Injective Functions for Multisets, Measures and Graphs via a Finite Witness Theorem [PDF]
, 2023 Tal Amir +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The Integer-antimagic Spectra of a Weak Join of Hamiltonian Graphs
Theory and Applications of GraphsA simple graph $G$ with vertex set $V(G)$ and edge set $E(G)$ is \emph{$\mathbb{Z}_{k}$-antimagic} if there exists a function $f: E(G) \to \mathbb{Z}_{k} \backslash \{0\}$ such that the induced function $f^+(v)=\sum_{uv\in E(G)} f(uv)$ is injective. The \
Ugur Odabasi +2 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source