Results 161 to 170 of about 14,925 (261)

Other science opportunities at the FCC-ee. [PDF]

Eur Phys J Plus
Agapov I, Alp EE, Andre K, Antipov S, Apyan A, Arduini G, Bandiera L, Bartmann W, Bartosik H, Benedikt M, Bettoni S, Byrd JM, Calviani M, Camper A, Carli C, Casalbuoni S, Chance A, Craievich P, Crivelli P, Dalena B, Dickmann M, Doser M, Drebot I, Duchemin C, Dupraz K, Frasca A, Freeman SJ, Gunsing F, Jäckel J, King B, Krasny MW, Lechner A, Lindstrøm CC, Mazzolari A, Milardi C, Musa E, Negrello R, Nguyen F, Oide K, Papaphilippou Y, Paternò G, Petrillo V, Piotrzkowski K, Rienäcker B, Schnell G, Schroer C, Schulthess I, Serafini L, Shiltsev V, Stampanoni M, Variola A, Watson T, Wienands HU, Wing M, Zimmermann F.   +54 more
europepmc   +1 more source

Optical Windows for Transcranial Brain Imaging in Living Mice: Skull Thinning, Clearing, and Beyond

Advanced Science, EarlyView.
Longitudinal, noninvasive in vivo imaging is crucial for studying brain physiology. Advances in transcranial optical windows and multiphoton microscopy have improved imaging depth, but their performance often deteriorates over time. This work investigated various transcranial window approaches and found that skull regrowth limits image quality.
Yiming Fu, Gewei Yan, Zhentao She, Yingzhu He, Kangqi Liu, Jianan Qu   +5 more
wiley   +1 more source

Investigation of the Optimal Duration and Modality for Postoperative Surveillance of Intraductal Papillary Mucinous Neoplasm (IPMN): A Single-Center Retrospective Study. [PDF]

Diagnostics (Basel)
Ozawa A, Nara A, Yokoyama K, Tsuchiya J, Ban D, Tateishi U.   +5 more
europepmc   +1 more source

RBM12 Maintains Glioma Stem Cells by Activating Amino Acid‐Dependent mTORC1 Signaling via SLC7A5 mRNA Stabilization

Advanced Science, EarlyView.
This study shows that in glioma stem cells (GSCs), RBM12 recruits ALKBH5 to remove m6A from SLC7A5 transcripts, thereby enhancing mRNA stability, which elevates large neutral amino acid (LNAA) levels and activates mTORC1, promoting GSC proliferation, self‐renewal, and tumor growth.
Hong Lei, Wenlong Luo, Shu Zhou, Lihao Wan, Peng Ling, Zhihua Huang, Zhihua Qian, Chenfei Lu, Mengyue Guo, Zhen Xue, Jun Qin, Ningwei Zhao, Jianghong Man, Wenchao Zhou, Zhiqiang Dong, Shutong Xu, Zhipeng Zhou, Xiuxing Wang, Weiwei Tao   +18 more
wiley   +1 more source

Content Validity of the Hemophilia Device Handling and Preference Assessment Questionnaire - A Cognitive Debrief Study in Patients with Hemophilia and Their Caregivers. [PDF]

Patient Prefer Adherence
Rasmussen NK, Shah S, Tsai JH, McCarrier KP, Hildebrand EA, Gonczi M, Ter-Borch G, Berg B, Neergaard JS.   +8 more
europepmc   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

A Rare Variation of Coeliac Trunk Hexafurcation. [PDF]

Diagnostics (Basel)
Triantafyllou G, Arkoudis NA, Velonakis G, Samolis A, Lyros O, Kokoropoulos P, Piagkou M.   +6 more
europepmc   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source

Design of an automated cell batch microinjection system based on magnetic tweezers for zebrafish embryos. [PDF]

Microsyst Nanoeng
Guo X, Wang F, Zhao A, Zhang Y, Jiang H, Knoll A, Shen M, Lv F, Zhou M.   +8 more
europepmc   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source