Results 171 to 180 of about 5,480 (246)

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

Other science opportunities at the FCC-ee. [PDF]

Eur Phys J Plus
Agapov I, Alp EE, Andre K, Antipov S, Apyan A, Arduini G, Bandiera L, Bartmann W, Bartosik H, Benedikt M, Bettoni S, Byrd JM, Calviani M, Camper A, Carli C, Casalbuoni S, Chance A, Craievich P, Crivelli P, Dalena B, Dickmann M, Doser M, Drebot I, Duchemin C, Dupraz K, Frasca A, Freeman SJ, Gunsing F, Jäckel J, King B, Krasny MW, Lechner A, Lindstrøm CC, Mazzolari A, Milardi C, Musa E, Negrello R, Nguyen F, Oide K, Papaphilippou Y, Paternò G, Petrillo V, Piotrzkowski K, Rienäcker B, Schnell G, Schroer C, Schulthess I, Serafini L, Shiltsev V, Stampanoni M, Variola A, Watson T, Wienands HU, Wing M, Zimmermann F.   +54 more
europepmc   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Surgical technique to prevent malposition of the Hydrus glaucoma microstent (The "gap sign"). [PDF]

Indian J Ophthalmol
Andrew NH, Habib M.
europepmc   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source

Twelve-Month Outcomes of iStent Infinite in Severe Open-Angle Glaucoma Compared with iStent Inject W in Mild-to-Moderate Disease. [PDF]

J Clin Med
Han S, Kim SW.
europepmc   +1 more source

Red Blood Cells as Endogenous Biotweezers for Optical Micromanipulation In Vivo

Advanced Science, EarlyView.
By synergistically integrating the long‐distance manipulation fiber probe (LDMFP) and endogenous red blood cells (RBCs) as biocompatible optical elements, a natural RBC biotweezer was developed for the desired microparticle manipulation and immune cell activation within living vasculature, which might offer an alternative tool for intravital optical ...
Tong Yang, Xinyu Ren, Dalin Ma, Hao Pang, Wei Chen, Kaize Cai, Mei Yuan, Bingzhi Zhang, Zufang Lin, Xiaoshuai Liu   +9 more
wiley   +1 more source

Surgical repositioning of a SING IMT following haptic dislocation: Restoration of alignment and visual function. [PDF]

Am J Ophthalmol Case Rep
Ameli S, Ní Dhubhghaill S, Vidal-Aroca F, Fasolino G.   +3 more
europepmc   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Visual Performance and Refractive Stability of Clareon^® Monofocal Intraocular Lens Implanted with an Automated Delivery System. [PDF]

Clin Ophthalmol
Tran E, Shah N, Caballero Ortiz S, Kyveris A, Berg G, Chan T.   +5 more
europepmc   +1 more source