Results 51 to 60 of about 11,092 (338)

Prospective unmasked randomized evaluation of the iStent inject (®) versus two ocular hypotensive agents in patients with primary open-angle glaucoma. [PDF]

open access: yes, 2014
PURPOSE: The purpose of this study was to compare outcomes of subjects with open-angle glaucoma (OAG) not controlled on one medication who underwent either implantation of two iStent inject (®) trabecular micro-bypass devices or received medical therapy ...
Anselm Juenemann   +8 more
core   +4 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Relationship of lifestyle and body stature growth with the development of myopia and axial length elongation in Taiwanese elementary school children

open access: yesIndian Journal of Ophthalmology, 2014
Context: The development of myopia and growth of the eye, occur at a time when body stature is increasing. Aims: To investigate the relationship of lifestyle and body growth with axial elongation and myopia development among schoolchildren aged 7 to 9 ...
Chung-Ying Huang   +4 more
doaj   +1 more source

Microwave Discharge Ion Sources

open access: yes, 2014
This chapter describes the basic principles, design features and characteristics of microwave discharge ion sources. A suitable source for the production of intense beams for high-power accelerators must satisfy the requirements of high brightness ...
Celona, L.
core   +1 more source

Evaluation of a new soft tipped injector for the implantation of foldable intraocular lenses [PDF]

open access: yesBritish Journal of Ophthalmology, 2006
To evaluate the R-INJ-04 soft-tipped injector, a new injector with an integral round nozzle manufactured by Rayner Intraocular Lenses, England.16 Rayner C-flex intraocular lenses (IOLs; Rayner Intraocular lenses, England) ranging between +10 and +30 D (2 for each power) were tested. An ophthalmic viscoelastic device (Healon, AMO, Santa Ana, California,
Guy, Kleinmann, David J, Apple
openaire   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Comparison of intracameral dexamethasone and intracameral triamcinolone acetonide injection at the end of phacoemulsification surgery

open access: yesIndian Journal of Ophthalmology, 2014
Purpose: To compare the results of intracameral dexamethasone and intracameral triamcinolone acetonide injection in patients that underwent cataract surgery with phacoemulsification.
Sirel Gur Gungor   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Intraoperative floppy iris syndrome in Indian population: A prospective study on incidence, risk factors, and impact on operative performance

open access: yesIndian Journal of Ophthalmology, 2014
Purpose: The purpose of this study was to evaluate the incidence, risk factors, and impact of intraoperative floppy iris syndrome (IFIS) on surgical performance.
Shilpa Goyal   +6 more
doaj   +1 more source

A comparative, observational study evaluating dosing characteristics and ovarian response using the recombinant human follicle-stimulating hormone pen injector with small-dose dial in assisted reproductive technologies treatment in Asia: IMPROVE study

open access: yesReproductive Biology and Endocrinology, 2022
Background Ovarian stimulation during medically assisted reproduction treatment should be individualized to optimize outcomes and reduce complications.
Bum Chae Choi   +10 more
doaj   +1 more source

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