Results 91 to 100 of about 1,867,682 (297)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Letter to the Editor: Analysis of Functional and Radiological Outcome Following Lumbar Decompression without Fusion in Patients with Degenerative Lumbar Scoliosis [PDF]

Asian Spine Journal, 2020
Tarush Rustagi, Abhinandan Reddy, Rajat Mahajan, Kalidutta Das, Harvinder Singh Chhabra   +4 more
doaj   +1 more source

Risk of total/subtotal meniscectomy for respective medial and lateral meniscus injury: correlation with tear type, duration of complaint, age, gender and ACL rupture in 6034 Asian patients

BMC Surgery, 2017
Background To evaluate the risk factor associated with total or subtotal meniscectomy for respective medial and lateral meniscus injury. Methods The data of all the meniscus injured patients undergoing arthroscopy in our institute between January 15th ...
Dong Jiang, Xiao Luo, Yingfang Ao, Xi Gong, Yong-jian Wang, Hai-jun Wang, Yu Miao, Nan Li, Ji-ying Zhang, Jia-kuo Yu   +9 more
doaj   +1 more source

The Independent Newspapers Limited study: an investigation into occupational overuse syndrome within the newspaper industry : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

, 1993
An investigation was undertaken into occupational overuse injuries. Overuse injuries are commonly associated with repetitive movements, sustained or constrained postures, and forceful movements. Other factors, such as work environment, amount of keyboard
Pirie, Ross
core  

Critical-Sized Bone Defects: Sequence and Planning. [PDF]

, 2017
Bone defects associated with open fractures require a careful approach and planning. At initial presentation, an emergent irrigation and debridement is required.
Abell, Apostle, Benson, Blum, Bosse, Breccia, Brewster, Brumback, Burston, Carver, D'Alleyrand, Dedmond, Dellinger, Dumbre Patil, Fischer, Fleming, Gerken, Gustilo, Gustilo, Henley, Hoff, Jenkinson, Johnson, Kao, Kirkup, Lack, Lee, Lee, Luchette, Mnif, Mohammad, Morelli, Moues, Murray, Palmer, Papakostidis, Patzakis, Patzakis, Pollak, Redfern, Rodriguez, Smith, Stannard, Templeman, Tornetta, Webb, Yaremchuk, Zalavras   +47 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Selective Use of Pericardial Window and Drainage as Sole Treatment for Hemopericardium from Penetrating Chest Trauma [PDF]

, 2018
Background Penetrating cardiac injuries (PCIs) are highly lethal, and a sternotomy is considered mandatory for suspected PCI. Recent literature suggests pericardial window (PCW) may be sufficient for superficial cardiac injuries to drain hemopericardium
Chestovich, Paul J., MD, Clark, Esmeralda, Fildes, John J., Fraser, Douglas R., Kuhls, Deborah A., McNicoll, Christopher F., Patel, Purvi P.   +6 more
core   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source