Results 51 to 60 of about 1,196,425 (308)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Primary care providers' discussion of fall prevention approaches with their older adult patients—DocStyles, 2014

Preventive Medicine Reports, 2018
Falls are the leading cause of fatal and non-fatal injuries among older adults. The American and British Geriatric Societies recommend a fall risk assessment to identify risk factors and guide interventions to prevent these falls.
Elizabeth R. Burns, Yara K. Haddad, Erin M. Parker   +2 more
doaj   +1 more source

Risk Factors Involved in Cheerleading Injuries [PDF]

, 2016
Injury prevention is an important aspect of health in which professionals in the field must focus. With a continual increase of risk in activities performed nationwide, health professionals must seek to educate the population on risk factors involved in ...
DeFreece, Kelsey
core   +2 more sources

National survey of the injury prevention activities of children's centres [PDF]

, 2013
Children's centres were established across England to provide a range of services including early education, social care and health to pre-school children and their families.
Audit Commission/Health Care Commission, Avis, Baggott, Belson, British Medical Association, Child Accident Prevention Trust, Children Schools and Families Committee, Cook, Department for Children Schools and Families, Department for Education, Department of Health, Department of Health, Edwards, Her Majesty's Treasury, Hogg, Hutchings, Kendrick, Litwin, MacNeill, McColl, Melhuish, Melhuish, National Institute for Health and Clinical Excellence, National Institute for Health and Clinical Excellence, National Institute for Health and Clinical Excellence, Oppenheim, Salant, Scriven, Speller, Stone, The National Evaluation of Sure Start Research Team, Towner, Walter, Watson, Watson, Watson, World Health Organization, World Health Organization, World Health Organization   +38 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Outcomes after angiography with sodium bicarbonate and acetylcysteine [PDF]

, 2018
Background: Intravenous sodium bicarbonate and oral acetylcysteine are widely used to prevent acute kidney injury and associated adverse outcomes after angiography without definitive evidence of their efficacy.
,, Androsenko, Maria, Bhatt, Deepak L., Brophy, Mary, Cass, Alan, Chertow, Glenn M., Conner, Todd A., Ferguson, Ryan, Gallagher, Martin, Garcia, Santiago, Jneid, Hani, Kaufman, James, McFalls, Edward O., Myles, John, Palevsky, Paul M., Parikh, Chirag R., Shunk, Kendrick, Thwin, Soe-Soe, Weisbord, Steven D., Wu, Hongsheng   +19 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

“It’s just what’s around these days”: social and contextual pragmatism in substance transitions

Harm Reduction Journal
Background The overdose epidemic is presently driven by polydrug use, sparking renewed interest in why people initiate use of certain drugs or drug combinations. Current research privileges the physiological ends of consumption, often ignoring the social
Adams L. Sibley, David C. Colston, Elizabeth Joniak-Grant, Hillary L. Mortensen, Monica E. Swilley-Martinez, Brian W. Pence, Shabbar I. Ranapurwala   +6 more
doaj   +1 more source

Racial and ethnic differences in fatal child abuse and neglect and the intersection of community poverty: U.S., 2003 to 2022

Child Protection and Practice
Introduction: In the U.S., child abuse and neglect (CAN) is a significant public health problem. Poverty is a well-known correlate of CAN. Objective: Examine racial and ethnic differences in fatal CAN among U.S. children and the intersection of community
Rebecca F. Wilson, Xin Yue, Karen E. Thomas, Krishna Kiran Kota, Carter J. Betz   +4 more
doaj   +1 more source

The impact of geographical location on trends in hospitalisation rates and outcomes for fall‐related injuries in older people

Australian and New Zealand Journal of Public Health, 2016
Objective: This population‐based study investigates the influence of geographical location on hospital admissions, utilisation and outcomes for fall‐related injury in older adults, adjusting for age, sex and comorbidities.
Dharan W. Sukumar, Lara A. Harvey, Rebecca J. Mitchell, Jacqueline C.T. Close   +3 more
doaj   +1 more source