Results 81 to 90 of about 1,155,302 (309)

A profile of adult patients with major burns admitted to a Level 1 Trauma Centre and their functional outcomes at discharge: A retrospective review

open access: yesSouth African Journal of Physiotherapy, 2022
Background: Patients with major burns suffer with pain, which impacts their physical function during hospitalisation. Objectives: To describe the demographics, burn characteristics, clinical course, physical function, complications developed after major
Irene K. Angelou   +3 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Leukocytosis as a Predictor of Severe Injury in Blunt Trauma

open access: yesWestern Journal of Emergency Medicine, 2008
Objective: The objective of this study was to determine if the white blood cell count can predict severity of injury in blunt trauma victims.Methods: This was a retrospective study comparing two groups of blunt trauma victims by severity of injury, one ...
Santucci, Claudia A   +2 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Correlating Various Clinical Outcomes and Associated Dispositions in Patients with Severe Traumatic Brain Injury (TBI)

open access: yesLife
Background: Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Patient disposition following TBI has been shown to interact with factors such as age, sex, and injury severity to impact clinical outcomes.
Bharti Sharma   +15 more
doaj   +1 more source

Trajectory and Determinant of Functional Independence Among Patient with Traumatic and Non-Traumatic Spinal Cord Injury [PDF]

open access: yes, 2018
The level of functional independence was directly proportional to life satisfaction and quality of life in patients with spinal cord injury. By knowing the determinants that predict changes in functional independence, medical treatment and rehabilitation
Ferdiana, A. (Astri)   +5 more
core  

Improving scope sensitivity in contingent valuation: joint and separate evaluation of health states [PDF]

open access: yes, 2017
We present data of a contingent valuation survey, testing the effect of evaluation mode on the monetary valuation of preventing road accidents. Half of the interviewees was asked to state their willingness to pay (WTP) to reduce the risk of having only 1
Abellán-Perpiñán, José María   +4 more
core   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Truck-involved crash severity in Thailand: a multilevel perspective on driver behavior and contextual influences

open access: yesFrontiers in Built Environment
Truck-involved crashes in Thailand frequently lead to severe consequences due to the vehicles’ large size, heavy loads, and high-speed operations.
Supanida Nanthawong   +6 more
doaj   +1 more source

Sequential Wnt Agonist then Antagonist Treatment Accelerates Tissue Repair and Minimizes Fibrosis [PDF]

open access: yes, 2019
Tissue fibrosis compromises organ function and occurs as a potential long-term outcome in response to acute tissue injuries. Currently, lack of mechanistic understanding prevents effective prevention and treatment of the progression from acute injury to ...
Fu, Haiyan   +7 more
core   +2 more sources

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