Results 121 to 130 of about 339,225 (252)

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

Predicting the Trauma and Injury Severity Score (TRISS) in patients admitted to trauma centers after trauma: A modeling study based on data from the French National Programme for Medicalization of Information. [PDF]

PLoS One
James A, Hajage D, Simon-Tillaux N, Tezenas du Montcel S, Rufat P, Riou B, Raux M.   +6 more
europepmc   +1 more source

Frequency of posttrauma complications during hospital admission and their association with Injury Severity Score. [PDF]

Clin Exp Emerg Med, 2023
Dasdar S, Yousefifard M, Ranjbar MF, Forouzanfar M, Mazloom H, Safari S.   +5 more
europepmc   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Epidemiological characteristics of pediatric trauma and the role of the Injury Severity Score in predicting mortality risk: a multicenter study. [PDF]

Eur J Pediatr
Bao Y, Zhao X, Guan L, Dai L, Tan L.
europepmc   +1 more source

Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu, Tianxue Chen, Wei Jin, Weifeng Jin, Haitong Wan   +4 more
wiley   +1 more source

Comparative evaluation of rapid emergency medicine score (REMS) and emergency trauma score (EMTRAS) against traditional trauma scoring systems-namely the injury severity score (ISS), new injury severity score (NISS), revised trauma score (RTS), and trauma and injury severity score (TRISS) in predicting trauma outcomes. [PDF]

Int J Crit Illn Inj Sci
Moorthy DGSRK, Rajesh K, Prasad KJD.
europepmc   +1 more source

Diffusion Basis Spectrum Imaging of Tissue Microstructure and Early Treatment in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Conventional MRI cannot resolve the coexisting pathological processes within multiple sclerosis tissue. Diffusion Basis Spectrum Imaging decomposes the diffusion signal into fiber, cell, and hindered ratios indexing axonal integrity, cellularity, and extracellular space, respectively.
Apisit Kaewsanit, Aime Luna, Bradley Judge, Nicole Shelley, Karl Friedrichsen, Jayashree Rajamanickam, Zhude Tu, Yong Wang, Tammie L. S. Benzinger, Qing Wang, Matthew R. Brier   +10 more
wiley   +1 more source

Improving Blunt Thoracic Trauma Prognosis: Validation of the Study of the Management of Blunt Chest Wall Trauma Score against Injury Severity Score in an Indonesian Tertiary Hospital. [PDF]

J Chest Surg
Isharanto A, Suhanda EY, Bayuadi IS, Wardhana KK, Damanik GRE, Muttaqin C.   +5 more
europepmc   +1 more source